AP 101 Final Flashcards
Layers of Epidermis and cells
Epidermis composed of epitheal tissue
Thicker CT = Dermis
Subcutaneous = Areolar + Adipose Tissue
Define Keratinocytes
stratified squamous epithleam
Produce keratin protein and lamelluar granules
90% epidermal cells
Melanocytes
Produce pigment melanin
8% of epidermal cells
Langerhans Cells
Red Bone marrow
immune system recognition
Damaged by UV light
Merkel Cells
Detect touch sensation
5 layers of epidermis in order thin
Basale, Spinosum, Granulosum, Corneum
5 layers of thick epidermis
Basale, Spinosum, Granulosum, Lucidum, Corneum
Basale
Basal = Base
Cuboidal columnar kertinocytes
Melano cytes + Merkel Cell
Spinosum
Spinosum = thorn like
langerhan cell metancoyte
Granulosum
Granulos = little grains
tonofilament abundance
keratohylin protein
lameller granules
Lucidum
Lucid = Clear
Only present in THICK skin
dead keratinocytes
Corneum
Corne = horn structure
within cells keratin
between cells lipids
What is keratinization
Accumulation of keratin as cells move from
one epidermal to the next
occurs in S basale
Growth of epidermis?
4 weeks (Formation and migration)
Vascular supply from dermis
Cells in S basale most active. produce keratinocytes
Composition papillary4 and reticular 5
Papillary - Consists of areolar connective tissue Dermal papillae consist of Capillary loops Meissner corpuscles Free nerve endings
Retitcular-
consist of DENSE Irregular connective tissue
Fibroblast, collagen, elastic fibers
strength extensibility elasticity
Function of Sebaceous Glands (Oil)
Keeps hair moist
Prevents excessive evaporation
inhibits growth of bacteria
Function of Sudoriferous Glands
2 main types = Eccrine & apocrine
Eccrine is outwards Merocrine
Regulates Temperature
Elimination of waste
Emotional Sweating
Apocrine is Seperate from,
emotional sweating
sexual activity
no role in thermal regulation
Ceruminous Glands
Sweat Glands in the ear
produces wax lubricant with ear hairs provides sticky barrier
waterproof canals
prevents bacteria from entering cell
Functions of the skin
Thermoregulation Blood reservoir Protection Cutaneous sensation Excretion vs absorption Synthesis of Vit D
Cutaneous vs Tactile
Cutaneous - stimulate skin surface very superficial
Tactile, Thermal, Pain and proprioceptive
Tactile
Tactile sensation
Touch - Pressure - Vibration - Itch Tickle
Recepters in the skin
Thermo Recepters
Free nerve ending
Thermation sensation
detected by cold n warm recepters
above 48 below 10
6 Function of Skeletal System
Bone osseous tissue Cartilidge DCT epitheleium Adipose Nervous tissue
2 types of bone marrow
Blood cell production = Red Bone Marrow
Triglyceride production = Yellow Bone Marrow
Define Homeopoises
the production of blood cells and platelets, which occurs in the bone marrow.
all bone marrow is red
Describe each part of long bone
Typical Components: Diaphysis Bone shaft or body – long, cylindrical, main portion of bone Epiphysis Proximal and distal portion of bone Metaphysis Regions bw the diaphysis and epiphysis In a growing bone – each metaphysis contains an epiphyseal (growth) plate – layer of hyaline cartilage that allows the diaphysis of the bone to grow in length
Articular cartilage
Thin layer of hyaline cartilage covering the part of the epiphysis where the bone forms an articulation (joint) with another bone
Reduces friction and absorbs shock at freely movable joints
Medullary cavity (marrow cavity)
Hallow, cylindrical space within the diaphysis that contains fatty yellow bone marrow in adults
Location and function of
Periosteum
Endosteum
Periosteum is located around the bone
protection and fracture repair
contains thick bundles of collagen fibers
endosteum - located inside the bone surface
single cell layers
small amounts of CT
what is Osseous Tissue
Bone contains extracellular matrix surrounding cells
water collagen mineral sale
Define calcification
Bone building Block/cells osteoblasts
Hardness vs flexibility
Harndess depends on inorganic mineral salts in the bone
Flexiliblity depends on collagen fibers n organic molecules in bone
4 types of bone cells
Osteo genic Cells - only cell that does cell division inside endo periosteum n canals
Osteo- Blasts, Building blocks , builds ECM of bone initiate calcification
Osteo- Cyte, Maintains and matures bone cells
Clasts - Breaks down in ECM lots in endosteum
Resporption.
Location function of compact tissue
under periosteum , protects supports resists, Osteons