Aortic dissection Flashcards
What is aortic dissection
Inner layer (intima) of aorta tears. Causes blood to surge through the tear causing the inner and middle layers (media) to separate. Causes a new false lumen and can lead to rupture
Where does aortic dissection most likely occur
First 10cm of aorta
What can weakening of aorta cause
Aneurysm or dissection
What is the DeBakey classification of aortic dissection
I- Intimal tear is ascending aorta and descending aorta is also involved
II- Only ascending aorta involved
III- Only descending aorta involved
What is Stanford classification of aortic dissection
A- Ascending aorta is involved (same as Debakey I and II)
B- Descending aorta is involved (same as Debakey III)
Complications of aortic dissection
- Blood flow from the false lumen can flow up the aorta back into the heart and into pericardial sac leading to pericardial tamponade
- Blood flowing through false lumen could puncture the tunica media and externa leading to rupture and haemorrhage into mediastinum
- The false lumen can also cause compression of nearby vasculature such as subclavian or renal artery leading to hypoxia of upper limbs or kidneys respectively
Risk factors for aortic dissection
Hypertension - main risk factor Smoking Hyperlipidaemia Thoracic AA Aortic Valve abnormalities Family History Previous cardiac surgery Trauma Cocaine/Amphetamine Use Connective Tissue Disease - eg. Ehlers-Danlos or Marfan’s
Aortic dissection signs and symptoms
Sharp chest pain- with radiation to back
Weak pulse in downstream arteries- Due to lack of blood flow to branched arteries
Difference in BP- difference between R and L arm
Hypotension
Shock- if there is rupture and significant blood loss
Investigations for aortic dissection
CXR- Would show widened mediastinum due to widened aorta
Transoesophageal Echo - more sensitive
CT Angio- Give more detailed pic of blood vessels and tear in the vessels
Management
Similar to dealing with aneurysm
A-E and stabilise pt
Vascular team involved
MEdical managemet
Used if stable, chronic
Reduce BP using antihypertensives and B blockers
Surgical management
Emergency surgical repair if -Increasing aortic diameter -Compromise of major branches of aorta Impending rupture -Bleeding into thoracic cavity
-Surgical management involves resecting and replacing the area of the aorta with intimal tear