Anxiety/phobia/social anxiety Flashcards
Biological features
Saliva: flow decreases due to digestion slowing down.
Heart rate increases and breathing quickens to increase blood flow to muscles for increase respiration
Muscles tense preparing for fight/flight/freeze
Skin: body perspires to cool itself
Eyes: pupil dilate to increase vision
Mixed findings between anxious and non anxious controls
Prevalence
44% women, 34% men
(Kessler 05) - highest specific disorder (12.5%), social phobia (12.1%), PTSD (6.8%), GAD, panic disorder, OCD (1.6%). Higher in females than males apart from equal in OCD
Course and outcome
Persists over time, usually don’t grow out of it. Predicts range of disorders in adolescence e.g. depression/ subst. misuse and other anxiety disorders
Neg. impact on social/academic functioning
Vulnerability - genetics
Twin studies: 25-60% heritability for phobias, panic disorder and vulnerability to PTSD and OCD (Afifi 10).
Very few studies found genetic reason for dysfunctional biological factor which underpins process of regulating stress response
Short allele variant of h-HTTLPR
Regulates expression of serotonin transporter gene
Associated with increased amygdala activation in response to fearful faces (Hariri et al)
Risk factor for PTSD (Cie 09)
However, also vuln. fact. for depression & BPD
Neurobiology
Amygdala involved in emotional modulation of memory, evaluation of stimuli with affective significance
Excessive activity of limbic system normally inhibited be frontal cortex. GABA and serotonin facilitate communication between limbic system and frontal cortex.
Efficiency of GABA/reduced in anxiety dis. & increased by anti-anxiety drugs. Beta blockers (zopiclone) effective for those with anx. related tremor but day time sedation, psychomotor impairment, dependence and misuse, hinder/help
Temperamental - Kotov et al (10)
All anxiety disorders associated with N, low C (except specific phobia) and introversion (except specific phobia and GAD)
Diathesis stress - Turner & Lloyd (04)
stressful life events can activate underlying vulnerability to anxiety (N, genetics).
Retrospective study, N=1800, 6+ major life events and accumulating exposure to lifetime adversity, increased risk of depressive/anxious episodes.
Parental influences - Murray et al (08)
Maternal anxiety expressed at 10 months predicted infant avoidance at 14 months
Specific phobia -
Intense fear when faced with specific stimulus which is out of proportion to danger posed. Objects avoided/tolerated with intense fear. Contact/entry = catastrophe.
Chapman - Most common: dental (3-5%), blood-injury (3.5%), water (3.3%), animals (1.1%)
Classical conditioning (behavioural) - Watson & Rayner
‘Little Albert’ - 11 month old Albert paired pet rat (CS) with loud noise (UCS). CR was crying when rat presented.
Traumatic experiences responsible for acquisition of some phobias (Dental phobia - Davey et al 89), choking (Greenberg et al 88)
Mowrer (39) - 2 factor theory
CC and Operant conditioning
Operant: conditioned fear response does not distinguish because avoidant behaviour negatively reinforced each time previously neutral stimuli avoided
Criticisms
Some stimuli produce CR easier than others
Many phobias can’t recall trauma (UCS)
Phobias learnt through observational learning/avoidance
Fear of situations can be observed without any avoidance e.g. military situations feared but not avoided
Eysenck addition (79) - biological preparedness
Incubation: fear increases in magnitude over successive encounters of trigger. Fear of fear itself reinforces phobic stimulus.
Constitutional vulnerability due to high levels of N and introversion
ERP and response
Exposure to feared stimuli and response prevented in order to habituate and anxiety response extinguished.
Nonfearful pairing generated through repeated encounters with feared stimuli without aversive consequences
Aim of treatment: establish a new association between stimuli and lack of fear. Also ensure maximum retrievability of this new association