Anxiety Disorders Flashcards
When do anxiety disorders tend to begin and how do they progress over a lifetime?
Tend to begin early teens or early 20s, waxing and waning over the course of a lifetime
What is the adaptive function of anxiety?
An alerting signal which helps prevent consequences
-> helps motivate and improve performance in moderate doses
What are the two components of anxiety and what is it critical to determine?
- Physiological sensations - i.e. palpations
- Feeling of nervousness or fright
Important to determine which comes first and causes the other symptoms
What is the neurochemical model of the etiology of anxiety?
Anxiety comes from activation of the autonomic nervous system, either primarily or secondary to a learned stimulus
-> causes release of NE, 5-HT, and GABA
What is the neuroendocrine model of anxiety etiology? Best piece of evidence?
HPA axis dysregulation accounts for anxiety
Cortisol levels are overly suppressed in PTSD
What is the genetic model of anxiety? What is one type of anxiety where this holds true?
Higher rate of concordance between monozygotic vs dizygotic twins
Finding: Specific phobias were more likely to occur within a family (although all these specific phobias may be different)
What is the psychodynamic model of anxiety and was it ever supported?
Anxiety is viewed as a signal of danger in the unconscious -> never supported (id vs superego idea)
What is the behavioral vs cognitive-behavioral anxiety model?
Behavioral - anxiety is a conditioned response to specific environment stimuli
Cognitive-behavior - adds on to the behavioral model by saying cognitive distortions / automatic thoughts guide our response to these environmental stimuli -> we overestimate the danger and underestimate the coping skills
How are agora and specific phobias treated with therapy? OCD?
Agora / specific phobias - Exposure with graded desensitization
OCD - Exposure plus response prevention
What are a couple types of medications which are known to precipitate anxiety?
Corticosteroids (also in inhalers)
Oral contraceptives
Others which are obvious dont be an idiot
What should you always give a patient who comes in with anxiety and what do you tell them?
Always give them a definitive diagnosis and some reading material to go over later when they are at home
Tell them side effects of the drugs and to come back in 7-10 days to make sure they’re adherent
What are the diagnostic criteria groups for panic disorder?
- Recurrent panic attacks
or - At least 1 month of persistent concern of having another panic attack, causing behavioral change
Typical other DSM criteria
If you have a panic attack do you have panic disorder? What is it often comorbid with?
No, must be recurrent or associated with significant worry / behavioral change
Better than 50% will have depression
What part of the brain is responsible for anticipatory anxiety? What types of anxiety manifestations do the following brain areas cause: prefrontal cortex? brain stem?
Amygdala / limbic system
Prefrontal cortex is responsible for avoidance behaviors
Brain stem: autonomic symptoms
What types of diseases are typically on the differential diagnosis for anxiety / panic disorders?
Cardiovascular / respiratory dysfunction to cause the physiological symptoms, endocrine dysfunction for stress hormones, etc
What, in general, are the diagnostic criteria for agoraphobia?
Fear of public spaces where escape might be difficult or help unavailable for greater than 6 months.
Anxiety is out of proportion to the actual threat posed, and thus these situations are avoided or endured with extreme anxiety
What are the pharmacotherapeutic interventions for panic disorder and agoraphobia / specific phobias?
Panic disorder - SSRIs are first line
Agoraphobia / panic disorders - exposure therapies, no pharmacotherapeutics indicated
What is the most common type of anxiety disorder and a very classic subtype?
Specific phobia disorder - causes panic attacks during exposure or anticipation of exposure
Blood-illness-injury phobia is classic -> vaso-vagal passing out due to shots
What, in general, is social anxiety disorder? What is the normal age of onset?
A fear or avoidance of social / interactional situations which lasts more than 6 months, can be as small as eating / using bathroom in public
Typically in teen years