Anxiety Disorders Flashcards
Symptoms of specific phobia must last at least this long, according to the DSM-5 criteria
6 months
What is the first line treatment for specific phobia?
Cognitive behavioral therapy / psychotherapy
Are males or females more likely to have generalized anxiety disorder?
Females (2x as common)
People of this descent are more likely to have generalized anxiety disorder
European
DSM-5 criteria for generalized anxiety disorder is that it must occur for at least this long
6 months
Is generalized anxiety disorder related to a single trigger?
No
The DSM-5 criteria for this condition is that it must be associated with three or more of the following:
Restlessness or feeling keyed up or on edge
Being easily fatigued
Difficulty concentrating or mind going blank
Irritability
Muscle tension
Sleep disturbance
Generalized anxiety disorder
What is the most effective treatment for generalized anxiety disorder?
Psychotherapy
When is pharmacotherapy used for generalized anxiety disorder?
When GAD is serious enough to produce functional disability
What is the difference between generalized anxiety disorder and adjustment disorder in regards to how long it lasts?
GAD lasts 6+ months
Adjustment disorder develops within 3 months of known stressor (resolves within 6 months)
What are the first line drugs for generalized anxiety disorder?
SSRIs and SNRIs
(e.g. duloxetine)
Benzodiazepines target GABA-A receptor, which has this effect on chloride channels
Increases frequency of chloride channel opening
Is diazepam short or long acting?
Long acting
(half life 30-100 hours)
Are benzodiazepines used for generalized anxiety disorder?
Are second line drugs - largely replaced by antidepressants for anxiety
Paradoxical excitement (mostly in children and elderly) can occur as a side effect of this type of drug which is a second line therapy for generalized anxiety
Benzodiazepines
Buspirone is a partial agonist of this receptor
5-HT1A
This second line drug for generalized anxiety disorder is a partial agonist of the 5-HT1A receptor
Buspirone
Is there misuse potential with Buspirone?
No
Will not affect cognitive or psychomotor function
(contrast to benzos)
Buspirone interacts with this type of drug, and can cause elevated BP and serotonin syndrome
MAOIs
Buspirone is a second line therapy for this disorder
Generalized anxiety disorder
Hydroxyzine is a second line therapy for this disorder
Generalized anxiety disorder
Condition characterized by series of unexpected/spontaneous panic attacks involving intense, terrifying fear
Generally followed by period of fear for another panic attack
Panic disorder
DSM-5 criteria of this condition requires four or more of the following symptoms:
Palpitations, pounding heart, or accelerated heart rate
Sweating
Trembling or shaking
Sensations of shortness of breath or smothering
Feelings of choking
Chest pain or discomfort
Nausea or abdominal distress
Feeling dizzy, unsteady, lightheaded, or faint
Chills or heat sensations
Paresthesias
Derealization or depersonalization
Fear of losing control or “going crazy”
Fear of dying
Panic disorder
Complications of this type of anxiety disorder include increased risk of alcohol use disorder, depression, suicide attempts, and excessive use and dependence on healthcare services and resources
Panic disorder