anxiety disorders Flashcards

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1
Q

anxiety facts

A

-approx18% in US -> >40 mil adults
-treated by PCP 90% of time
-high rates of comorbid psychiatric disorders, especially Depressive Disorder (50%)
-High rates of comorbid alcohol and drug abuse
-high rates of suicide attempts
-MC mental health illness in USA
-5X more likely to seek medical care for a variety of conditions
-6X more likely to be hospitalized for a psychiatric condition
-Affects 1/8 children -> strong genetic component
-Children -> increased risk of truancy, substance abuse, being bullied and poor school performance

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2
Q

anxiety as normal and abnormal response

A

-Some amount of anxiety is “normal” and is associated with optimal levels of functioning.
-Adaptive response to threat to self or environment

-when anxiety begins to interfere with social or occupational functioning is it considered “abnormal.”
-can affect school, work, social relationships and physical health.

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3
Q

social effects of anxiety

A

-Prolonged anxiety can result in Major Depression
-less involved with family/friends the way you used to be
-Lowered quality of relationships
-Low energy, lethargy, dysphoria
-Lack of motivation to do the things you once looked forward to doing
-Unable to convey the person that you are
-Fear and avoidance of situations where previous attacks occurred

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4
Q

what is anxiety: clinically, anthropologically, psychiatrically

A

-Clinical Answer:
-unpleasant emotional and physical state characterized by fear, apprehension, restlessness, tension, over-activity of the autonomic nervous system, cardiac and pulmonary sensations, and the expectation of impending disaster.

-Anthropological Answer:
-“stress response” hardwired into the brain of most mammals triggered when survival is threatened.

-Psychiatric Answer:
-Catecholamines: Decreased activation of serotonin and increased activation of norepinephrine
-Increased autonomic activity: increases HR, BP, force of cardiac contractions, and dilates airways in lungs

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4
Q

what is anxiety disorder

A

-illness that often manifests with psychological and somatic symptoms

-produces:
-Intense, excessive, and prolonged states of apprehension and fear
-Autonomic arousal (elevated pulse, elevated BP, diaphoresis, rapid breathing)
-Physical discomfort (headache, dizziness, nausea, abdominal pain, diarrhea, myalgias, arthralgias)

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5
Q

developmentally normal fears

A

-birth-6 months- Loud noises, loss of physical support, rapid position changes, rapidly approaching other objects

-7-12 months- Strangers, looming objects, unexpected objects or unfamiliar people

-1-5 year- Strangers, storms, animals, dark, separation from parents, objects, machines with loud noises

-6-12 year- Supernatural, bodily injury, disease, burglars, failure, criticism, punishment

-12-18- Performance in school, peer scrutiny, appearance, performance

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6
Q

types of anxiety disorders

A

-Generalized Anxiety Disorder
-Social Anxiety Disorder
-Phobia
-Panic Disorders
-PTSD
-OCD

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7
Q

generalized anxiety disorder

A

-excessive anxiety and worry
-worry occurs more often than not for at least 6 MONTHS and is clearly excessive
-worry is very hard to control
-worry can shift from one topic to another

-anxiety are accompanied 3+ of following (in children, only 1 is necessary for dx of GAD):
-edginess or restlessness
-tiring easily, more fatigued than usual
-impaired concentration or feeling as though the mind goes blank
-irritability (may or may not be observed by others)
-increased muscle aches or soreness
-difficulty sleeping (due to trouble falling asleep, staying asleep, restlessness at night, unsatisfying sleep)

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8
Q

GAD example

A

Nick is a 52 yr old pharmacist who can’t remember a time when he was not feeling anxious. Although he is competent at his job, he gets extremely anxious about work and feels that he might make mistakes. This worry also extends to his personal life where he is always worrying about his kids academic performance and if they are getting bullied.
He often has nightmares and feels tired and restless all the time. Although he has a great marriage, he worries constantly that he may not be able to provide for his family which causes him to have sleepless nights

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9
Q

social anxiety disorder

A

-6 MONTHS or longer AND
-cause personal distress and impairment of functioning in 1+ domains -> interpersonal or occupational functioning

-anxiety specific to social settings
-person feels noticed, observed, scrutinized,
-men = women
-adults- first date, job interview, meeting someone for the first time, delivering an oral presentation, speaking in class or meeting
-children- settings with peers (NOT adult interactions), showing age appropriate distress -> cringing, crying, fear, discomfort
-fear that anxiety will display and have social rejection
-social interaction consistently provoke distress
-social interactions are avoided OR reluctantly endured
-anxiety will be grossly disproportionate to actual situation

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10
Q

social anxiety disorder example

A

-Bill is a 34 yr old accountant who was recently promoted to a mid level management position at his bank. Bill was wary about this promotion but felt he had not choice but to accept it. His fear stem from the fact that he has to make presentations to the senior management regarding projects his team is involved in.
-Weeks before any presentation, he has nightmares about how he might screw up, feels extremely anxious and his work starts suffering. Although he knows his anxiety is unreasonable, he just cannot help it.

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11
Q

phobic disorder

A

-unreasonable, excessive fear
-triggered by specific object or situation
-out of proportion to actual danger
-instantaneously reacts when presented with object or situation
-goes out of way to avoid or endures with extreme distress
-significantly impacts the individuals school, work, or personal life

-at least 6 MONTH duration
-not caused by another disorder- first need to rule out similar conditions -> agoraphobia, OCD, separation anxiety -> before dx specific phobia

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12
Q

phobia: subtypes

A

-Animal
-Natural environment
-Blood-injection-injury
-Situational
-Other
-The anxiety, panic attack, or phobic avoidance associated with the specific object or situation is not better accounted for by another mental disorder.
-Symptoms for all ages must have a duration of at least 6 months

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13
Q

phobic disorder example

A

-Phyllis works at her dream job as a marketing executive for a multinational firm. Recently her firm was acquired by another company which requires her to travel to distant sites for work reasons.
-Phyllis is extremely scared of flying due to a childhood incident when she endured extreme turbulence in an airplane, which led to an emergency landing. Her frequent attempts to delay flying to places has led to disciplinary action and she is seriously contemplating leaving her current job, which she loves.

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14
Q

agoraphobia

A

-Anxiety about being in places or situations from which escape might be difficult or embarrassing in event of a panic attack.
-Person engages in avoidance behaviors to avoid the fear and/or a related panic attack
-DSM 5: last more than 6 MONTHS
-Examples:
-Enclosed Places
-Driving
-Public Transportation
-Crowds
-Shopping Malls and Supermarkets

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15
Q

panic disorder

A

-Recurrent unexpected panic attacks
-abrupt surge can occur from calm or anxious state
-reaches peak within minutes, and during which time 4 (or more) of the following symptoms occur:
-Palpitations, pounding heart, or accelerated heart rate.
-Sweating.
-Trembling or shaking.
-Sensations of shortness of breath or smothering.
-Feelings of choking.
-Chest pain or discomfort.
-Nausea or abdominal distress.
-Feeling dizzy, unsteady, light-headed, or faint.
-Chills or heat sensations.
-Paresthesias (numbness or tingling sensations).
-Derealization (feelings of unreality) or depersonalization (being detached from oneself).
-Fear of losing control or “going crazy.”
-Fear of dying.

16
Q

panic disorder examples

A

-Bob is a 22 yr old college student what started feeling extremely anxious and felt he was having a heart attack at a stop light. There was no specific trigger he could identify prompting this sense of acute nervousness/fear. He was having difficulty breathing and the onset was abrupt.
-These feelings lasted about 15 mins and he seriously contemplated going to the nearest ED although he recognized he had feelings like this before. He always suffered from mild anxiety but these abrupt bouts of extreme nervousness were new to him.

17
Q

post traumatic stress disorder

A

-Criterion A:Exposure to death, threatened death, serious injury, or sexual violence in 1 (or more) of the following way(s):
-Direct experience of trauma
-Witnessing first hand trauma
-Learning relative/friend was exposed to trauma
-Repeated or extreme exposure to aversive details of trauma, typically experienced by first responders, medics, police officers, etc.

-Criterion B:Presence of 1 (or more) INTRUSIVE symptoms associated with the traumatic event(s) after the event(s) occurred:
-Recurrent distressing memories
-Recurring nightmares
-Flashbacks, or disassociative reactions in which person feels the trauma repeating
-Intense or prolonged psychological distress in the face of reminders
-Physical reactions in the face of reminders

-Criterion C:AVOIDANCE of stimuli associated with the trauma, as evidence by 1 or more of the following:
-Avoidance of distressing memories and thoughts about the trauma
-Avoidance of distressing external reminders of the trauma, like people, places, conversations, and activities

-Criterion D:Negative alterations to mood and cognition, as evidenced by 2 (or more) of the following:
-Inability to remember important aspects of the trauma
-Exaggerated negative thoughts about oneself, others, or the world
-Blaming oneself or others for the trauma
-Persistence negative emotional state, like fear, horror, anger, guilt, or shame
-Diminished interest in activities
-Feelings of detachment or estrangement from others
-Inability to experience positive emotions

-Criterion E:Alterations in arousal and reactivity, as evidenced by 2 or more of the following:
-Irritability and angry outbursts with little or no provocation
-Reckless and self-destructive behavior
-Hypervigilance- constantly assessing threats
-Exaggerated startle response
-Problems with concentration
-Difficulty sleeping

-Criterion F:Duration of the disturbance is > 1 month

-Criterion G:significant distress or impairment in social, occupational, and other important areas of functioning.

-Criterion H:Symptoms are not due to medication, substance use, or another medical condition

18
Q

PTSD domains

A

-Re-experiencing: Intrusive thoughts, images, flashbacks, nightmares, or stress from cues that remind one of the event

-Avoidance: Avoiding thinking/talking about the event, affective numbing, amnesia, derealization, depersonalization, restricted emotions (unable to have loving feelings)

-Negative Cognition/Mood: Anhedonia (everything is bland), difficulty remembering event, sense of self-blame

-Hyperarousal: Insomnia, hypervigilance, exaggerated startle response, difficulty concentrating, anger

19
Q

PTSD ex

A

-A 35 yr old Afghanistan war veteran has been having trouble sleeping at night. He often has nightmares and trouble driving especially in traffic. He cringes when he hears horns blasting and has been experiencing palpitations and diaphoresis.

These episodes started after completing 3 tours of duty in Afghanistan. His wife states he gets very irritable when asked about his war experiences and recently has been drinking a lot.

20
Q

obsessive compulsive disorder

A

-men = women
-1/3 have 1st sx in childhood

-Distressing, intrusive obsessive thoughts and/or repetitive compulsive physical or mental acts.

-Obsessions: Recurrent THOUGHTS, impulses, or images that are experienced as intrusive and inappropriate.
-The thoughts, impulses, or images are NOT simply excessive worries about real-life problems.

-Compulsions: Repetitive BEHAVIORS or mental acts that the person feels driven to perform in response to an obsession.
-They are meant to help the person ignore the obsession or decrease associated anxiety.

21
Q

obsessive compulsive anxiety and related disorders

A

-obsessive-compulsive disorder (OCD)
-body dysmorphic disorder
-trichotillomania (hair-pulling disorder)
-hoarding disorder
-excoriation (skin-picking) disorder

22
Q

OCD presentions

A

OBSESSIONS
-Contamination
-Pathologic Doubt
-Need for Symmetry
-Scrupulous- religion or morals
-Aggressive/Violent
-Sexual

COMPULSIONS
-Cleaning/Washing
-Checking
-Arranging
-Confessing
-Counting
-Praying

23
Q

OCD physical symptoms

A

-Eczematous eruptions: Caused by excessive washing
-Hair loss: Caused by compulsive hair pulling (trichotillomania)
-Excoriations: Caused by compulsive skin picking (neurodermatitis)
-Behaviors aimed at reducing anxiety and preventing some future dreaded event
-Elevated risk of suicidal ideation

24
Q

OCD example

A

19 year-old college freshman washes his hands at least 40-50 times each day. If he does not wash his hands, he becomes progressively more anxious. He also must open and close each door three times before entering or leaving a room. If he loses count, he must start all over.

Even though he calls his behavior “silly,” he is unable to stop. Because the behavior takes up so much of his day, his grades suffered. Subsequently, he had to take a leave of absence from his university.

25
Q

obsessive compulsive anxiety disorder vs obsessive compulsive personality disorder

A

-obsessive compulsive anxiety disorder - obsession that lead to compulsions
-distress

-obsessive compulsive personality disorder - need everything to be a certain way
-no distress
-they are happy to be like this
-it is there nature

26
Q

prevalence and age of onset of mental health disorders

A

-panic disorder -late teens/mid 30s- 1.5-3.5%

-specific phobia: 10-11.3%:
-situational- childhood/mid-20s
-natural environment- childhood/early adult
-animal- childhood
-blood/injection- childhood

-social phobia- mid teens- 3-13%
-OCD- 6-15yrsM/20-29yrs F- 2.5%
-GAD- childhood/adolesence- 5% THIS IS THE MOST COMMON! EXAM
-PTSD- any age- 1-14%

27
Q

what are risk factors for anxiety

A

-Genetics: up to 50% concurrence rate in monozygotic twins

-Familial Factors: Many anxiety disorders demonstrate a familial pattern
-First-degree relatives of pts with panic disorders have up to a 7-fold increased probability of having panic disorder

-Environment: Behavioral traits and coping mechanisms are learned consciously or subconsciously from family, friends, peers

-Stress: Loss of a loved one/employment/status/financial security; Scholastic/occupational/romantic failure

28
Q

anxiety screening process- eval

A

-History (medical and psychiatric)
-Medication review
-Physical examination
-Psychiatric interview
-Mental Status Exam
-Labs and Imaging studies

29
Q

how do we dx anxiety disorder

A

-proper hx
-social drug- alcohol, caffeine, nicotine
-prescription drugs- corticosteroids, beta agonist, theophylline, methylphenidate
-OTC drugs- decongestants
-illicit drugs- cocaine, amphetamine, marijuana, LSD, K2
-drug withdrawal- alcohol, caffeine, nicotine, benzodiazepines, beta blockers, heroin, pain meds

30
Q

screening questions for anxiety

A

-Have you ever experienced a panic attack? (Panic Disorder)
-Do you consider yourself a worrier? (GAD)
-Have you ever had anything happen that still haunts you? (PTSD)
-Do you get thoughts stuck in your head that really bother you or need to do things over and over like washing your hands, checking things or count? (OCD)
-When you are in a situation where people can observe you do you feel nervous and worry that they will judge you? (SAD)

31
Q

anxiety treatment: Psychotherapy

A

-CBT: Identify destructive thought patterns and behaviors
-Replace them with more realistic and helpful ones

-Relaxation Techniques: Meditation, yoga, progressive muscle relaxation, visualization

-Exposure and Desensitization: Gradually exposing Pt to avoided stimulus decreases the intensity of object of anxiety (Phobic Disorder, OCD)

-Response Prevention: Prohibiting the patient from performing anxiety reducing rituals decreases the intensity and frequency of the behavior (OCD)

32
Q

anxiety treatment: Pharmacotherapy

A

-SSRIs (Prozac, Lexapro): First Line Treatment!!!
-Starting dose is lower than for Depression -> Side effects are more common compared to Depression
-Therapeutic dose often higher than for Depression
-Side effects are more common than in Depression

-SNRIS (Effexor XR, Pristiq, Cymbalta): Indicated in Anxiety and Depression

-Tricyclic Antidepressants: Anafranil indicated for OCD

-Serotonin Partial Agonists (BuSpar): Indicated for GAD only
-No tolerance, dependence, withdrawal, and sedation

-Benzodiazepines: Not first-line tx, but, has more immediate onset.
-Side Effects: Sedation, confusion, impaired memory, ataxia, behavioral disinhibition, respiratory depression, tolerance, dependence, withdrawal
-May lead to death in pts with impaired respiratory function (COPD, Sleep Apnea)

-Antihypertensives:
-Alpha-2 Agonists (Clonidine): Reduces sympathetic activity
-Beta-blockers (Inderal) Decrease autonomic response (i.e. tachycardia, diaphoresis)

-Anticonvulsants (Neurontin, Lyrica): Increase GABA levels in the brain

-Antipsychotics (Risperdal, Geodon): Decrease dopamine in brain
-Block Serotonin-2 pathways in the brain

33
Q

anxiety/panic attack in emergency room setting

A

-Calm environment
-Supportive therapy
-Ativan 1.0-2.0 mg PO/IM/IV q 30 min PRN
-Can consider 1 time dose of antipsychotic
-SSRI first line long term therapy
-Prescribe benzodiazepines only on a short term basis
-Refer for CBT

34
Q

alternative tx

A

-Acupuncture
-Aromatherapy
-Breathing Exercises: 5/2/5 method
-Exercise
-Meditation
-Nutrition and Diet Therapy
-Vitamins
-Hobbies
-Volunteering