Anxiety Disorders Flashcards
WHat is the diff between fear & anxiety?
Fear - rxn to immediate danger; short-lived
Anxiety - anticipated problem; longer-lived
What DSM criteria is anxiety dosrder? What are these 5 disorders?
DSM-5
panic disorder
Agoraphobia
Specific phobias
social anxiety disorer
General anxiety disorder
What are the symptoms of anxiety disoders?
Core: Anxiety & worries
Assoc symptoms: fatigue, poor concentration, problems in sleep, irritability, muscle tension, phobic avoidance, compulsion
What are the contirbuting factors to anxiety disorders?
Psycho-anaytic
Behavioral
Existential
What is the psychoanalytic theory?
2 kinds:
Death wish
Life wish
If these are not expressed appropriately through either aggression, sports, or sexually, this libido gets stick & builds up —> anxiety
Result of a psychic condlict betw unconscious sexual or aggressive wishes with threats from the superego or external reality
What are the diff behavioral theories
Avoidance conditioning
Modeling
Interoceptive conditioning
Fear-of-fear
Social skills deficits
What is the modeling/social learning theory?
Fear may be learned through imitating the actions of others
What is interoceptive conditioning?
Panic attacks are seen as clasically conditioning of the person to interna lbodily sensations of anxiety
What are the causes of anxiety disorders accdg to anxiety phenotype?
Amygdala cetered circuit is hyperactive —> fear
Cortico-striato-thalamo-cortical loop —> anxious misery, apprehensive expectation, obsessions
What are the neurotransmitters that drive CSTC loop which is linked to “worry” symptoms?
Serotonin (5-HT)
Norepinephrine
Gamma-Aminobutyric acid (GABA)
What part of the brain releases 5-HT/Serotonin?
Raphe nuclei
LOW levels of circulating 5-HT
How does NRE mediate arousal?
- Relays msges in the sympathetic NS (fight or flight)
- Wakefulness and arousal to respond to stimuli —> vigilance
What happens to NRE levels/secretion in anxiety disorders?
Dysregulated noradrenergic function —> INC sympathetic nervous system activity
What happens to GABA that promotes anxiety disorders?
DEC GABA —> hyperarousa
What disorder refers to recurrent unexpected panic attacks?
Panic disorders
What are the 2 types of panic attack? What is the diff between them?
Cued - cause is known (situational trigger: phobia)
Uncued - recurrent in unexpected situations
What are bioogical correlations of panic disorder in brain imaging?
Blood flow dysregulation in the hippocampus and amygdala
What is then used to test for panic attacks where CO2, Na lactate & HCO3 INC CO2 and Lactate concentrations —> respiratory stimulation
Panicogens
What are the 4 DSM-5 criter for panic disorder?
Crterion A, B, C & D