Anxiety Disorders Flashcards
What is Generalised Anxiety Disorder (GAD)?
Excessive and uncontrolled anxiety about everyday things i.e. money, health, family, work, relationships.
Must be:
- Persistent
- Excessive
- Unreasonable
Describe the different severities of GAD
Mild > Normal social function
Severe > Difficulty with simple daily activities
What is the DSM-V diagnostic criteria for GAD?
- Excessive anxiety/worry about everyday issues for at least 6 months that is disproportionate to any inherent risk, and causes distress, or impairment
- Associated with 3 symptoms (1 in children)
Also - worry not due to mental disorder, substance abuse, other condition.
What is the aetiology of GAD?
Biological
- Genetic predisposition
Psychosocial
- Current stress, life events
- Childhood experiences (separations, demands for high achievement, excessive conformity)
- History of trauma
- Divorced
- Lone parent
- Living alone
- F > M
- Begin <25yrs
- Substance abuse
- Chronic painful illnesses
What are the S/S of GAD?
Psychological
- Frequent worry and tension
- Restlessness / edginess / irritability
- Impaired concentration / mind goes blank
Physical
- Insomnia / difficulty sleeping
- Muscle aches / pain / tension
- Constipation / diarrhoea / nausea
- Autonomic - palpitations / sweating / dry mouth / trembling / tachycardia / tachypnoea
- Difficulty breathing / choking sensation / CP
- Dizziness / light headedness / fear
> 3 required for diagnosis
What are the investigations for GAD?
- GAD-7 questionnaire (5 = mild, 10 = moderate, 15 = severe)
- Beck’s Anxiety Inventory
- HADS
- Bloods: FBC, U+Es, LFTs, Ca, TFTs
What is the management of GAD?
BIOPSYCHOSOCIAL stepwise approach
Step 1
Education & active monitoring
- Written information on GAD
- Online resources
- Regular exercise
Step 2
Low-intensity psychological interventions:
- Non-guided self-help (individual) > 6 weeks
- Guided self-help (individual) > 6 weeks
- Psychoeducational groups > 6 weeks
Step 3
High-intensity psychological interventions +/- medication
- CBT > 12-15 weeks
- Applied relaxation > 12-15 weeks
- SSRI (1st line NICE = sertraline; only SSRI licensed = paroxetine)
- Weekly follow-up due to increased risk of suicidal thinking / self-harm initially - Switch to another SSRI (after 8 weeks in step 1)
- Switch to an SNRI (venlafaxine)
- Weekly follow-up due to increased risk of suicidal thinking / self-harm initially - Pregabalin (antiepileptic) > modulate VGCC
Step 4
Highly specialist input
What is a phobia?
An anxiety disorder defined by a persistent and excessive fear of a specific object or situation.
Leads to avoidance of the feared situation, and can lead to disability.
What are the S/S of a phobia?
- Avoidance
- Fear
- Disability
What are the types of phobia?
- Social
- Specific
- Agoraphobia
What is the aetiology of a phobia?
- Genetics
- Can occur following major life event in someone with dependent personality traits
What is the ICD-10 definition of agoraphobia?
A phobia embracing fears of leaving home, entering shops, crowds and public places, or travelling alone in trains, buses or planes – literally means ‘fear of the marketplace’
Classified WITH or WITHOUT a panic disorder
What are some ‘problem situations’ for agoraphobia?
Travelling (trains, buses, etc.), queueing, supermarkets, crowds, parks
Describe the epidemiology of agoraphobia
- Age of onset = 20-35yo
- Onset often follows a precipitating event, which may be a panic attack, which leads to avoidance, or can be gradual
- F>M
What are the S/S of agoraphobia?
- Panic attacks
- Anxiety symptoms: palpitations, sweating, shaking, dry mouth, difficulty breathing, chest pain, nausea, dizziness, hot flushes, fear of losing control, fear of dying
- The patient may feel better if accompanied by someone else
- Becomes dependent on someone else
- Avoidance of phobic situations ± isolation behaviour
- Associated features: depressive/obsessional symptoms, social phobias
N.B. some agoraphobics may have little anxiety because they can avoid specific triggers well
What is the management of a phobia?
Step 1. = Education, reassurance and self-help
Step 2. = CBT with Exposure Response Prevention (ERP)
- ‘Desensitisation approach’
- (1) Pt. identifies goal (i.e. holding a slug) and constructs hierarchy of feared situations
- (2) Pt. tackles hierarchy from least to most frightening
- (3) Aim to stay in situation until anxiety subsided > challenges existing thoughts
Step 3. = Medication
- SSRIs
- Beta blockers
- Short-course BZN (only in urgent situations e.g. high risk to self / others, or for certain specific phobias i.e. dental injections)
Also:
- +/- Relaxation therapy and breathing techniques
What is a social phobia / social anxiety disorder?
Fear scrutiny by other people leading to avoidance of social situations - associated with low self-esteem
What is the difference between social phobia and agoraphobia?
People with SAD will tolerate anonymous crowds, unlike agoraphobics, but smaller groups may spike anxiety
What are the S/S of a social phobia / SAD?
- Blushing, hand tremor, nausea or urinary urgency in social situations (i.e. explore situations)
- Self-medicate with alcohol or drugs (to desensitise)
- Panic attacks
- Social withdrawal
- Alcohol abuse more common
What is a specific phobia?
Phobias restricted to highly specific situations such as proximity to slugs or snails.
Describe the epidemiology of specific phobias
- COMMON
- Begin in childhood
- F > M
- May have a FHx of phobia (indicating a negative reinforcement as a child or classical conditioning)
What are the S/S of a specific phobia?
- Contact can evoke panic (e.g. barricading bedroom, screaming at housemates)
- Most phobias lead to tachycardia, but blood or injury phobia cause an initial tachycardia followed by vasovagal bradycardia and hypotension > may cause nausea and fainting
Should you treat anxiety/phobias with BZN or antidepressants?
- NEVER treat anxiety with BZN as there is a high risk of dependence (short-term in specific phobia is ok)
- Specific Phobias do NOT respond well to antidepressants
What is the definition of panic disorder?
Sudden, unexpected, recurrent panic attacks not triggered by a specific stimulus, which give rise to excessive and dysfunctional anxiety, even between attacks.
What are the S/S of a panic attack?
- Fear of suffocating / dying
- Hyperventilation
- Sweating / dizziness / palpitations
- Chest discomfort
- Desire to flee
What are the S/S of panic disorder?
- Sudden, unexpected onset of panic attack
- Usually last ≤30 minutes (anywhere from 1 minute - 1 hour)
- Several within a month
- Alarming thoughts (i.e. I’m going to die) provoke further panic until reassurance or engagement in ‘safety behaviour’ occurs (i.e. call ambulance, take aspirin, etc.)
- In between episodes, relatively fine with minimal anxiety
> Panic disorder should not be main diagnosis if a depressive disorder exists at the time attacks start