Anxiety And Insomnia Flashcards
Barbiturates action
CNS depressants
Act in the reticular formation of the brainstem
Inhibit never impulse transmission by potentiating GABA action
Barbiturates uses
Anesthesia for short surgical procedures
Control convulsions
Reduce ICP in neuro patients
Prophylaxis of seizures
Barbiturates adverse effects
Less REM sleep Hangover feeling Dizziness Hypotension Nausea Respiratory depression
Short acting barbiturates
Pentabarbital
Secobarbital
Intermediate acting barbiturate
Butarbital
flumazenil
Romazicon
Reversal agent for benzos
Long acting barbiturates
Phenobarbital - prototypical
Mephobarbital
Benzodiazepines uses
Preferred med to treat anxiety and insomnia
Do not cause life threatening resp depression
Shorten time to fall asleep, less interrupted sleep
zolpidem
Ambien
Sleep
Nonbenzo
Benzos action
Affect type 1 and 2 GABA receptors - stimulate release of GABA
Schedule 4
Muscle relaxant uses
Relief of painful muscle spasm
Multiple sclerosis
Rx of malignant hyperthermia
Benzos uses
Sedation Decr anxiety Sleep induction Anxiety related depression Acute seizure disorders
Reduced memory when combined with anesthetics
Give 30 min before bed
Benzos adverse effects
Sedation, decreased alertness Hypotension Confusion Amnesia Agitation Hepatoxicity Tolerance Habituation
BuSpar
buspirone
Misc agent for anxiety
Benzos contraindications
Pregnancy/lactation - cat X
<18 years
Glaucoma