Anxiety Flashcards

1
Q

what are the 3 main areas that may cause anxiety?

A
  • Genetic
  • Environment (childhood, divorce, lifestyle)
  • Development
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

what are the subtypes of anxiety?

A

o Generalised anxiety disorder (GAD)
o Panic disorder
o Social phobia / social anxiety disorder (this is the main one)
o Obsessive compulsive disorder (OCD) [not examinable]
o Post-traumatic stress disorder (PTSD) [not examinable]
o Agoraphobia [not examinable]
o Other phobias [not examinable]

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

what are the psychological symptoms of anxiety?

A
	Worrying thoughts
	Fearful anticipation
	Poor memory
	Insomnia
	Poor concentration
	Avoidance behaviours
	Irritability 
	Sensitivity to noise and light
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

what are the physical symptoms of anxiety?

A
	Palpitations, SOB
	Tremor
	Sexual difficulties 
	Problems with urinary/faecal excretion
	Fatigue 
	Dizziness, headache
	Poor swallowing / dry mouth
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

how do you diagnose anxiety?

A
  • When someone presents with symptoms of anxiety, general screening can be performed with the generalised anxiety disorder scale (GAD-2) to determine whether further investigation is required
  • GAD-2 questions. How often have you experienced the following over the last 2 weeks?
  • Feeling nervous/anxious/on edge
  • Uncontrollable worrying
  • If they score above 3 they will be asked further questions
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

what are the specific symptoms of GAD?

A
  • excessive worrying about a number of issues
  • preoccupation, seeking reassurance
  • over arrousal and irritabiliity
  • insomnia
  • poor concentration
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

what are the specific symptoms of panic disorder?

A
  • worrying and fearful thoughts
  • surge of intense panic
  • poor memory
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

what are the specific symptoms of social anxiety?

A
  • overwhelming fear of social situations
  • excessive worrying
  • panic attacks
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

what are the psychological options of GAD?

A

 Education and active monitoring important first step
 Self-help (either non-facilitated or guided) and group education are considered as first line treatments for GAD if education ineffective
 High intensity psychological intervention can be used if group education/self help not effective or marked functional impairment
o CBT
o Applied relaxation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

what are the pharmacological options for GAD?

A

 Offered to those who have marked functional impairment or education/self-help not effective
Treatment choice:
 Selective Serotonin Reuptake Inhibitor (SSRI) first line – sertraline (unlicensed)
o Response increases over time
o If effective treat for one year
 Alternative SSRI or SNRI second line
 Offer pregabalin 3rd line
 Benzodiazepines for short term use only in severe anxiety state (crisis)
 DO NOT use antipsychotics

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

what are the psychological therapy options for panic disorder?

A

 Offer individualised cognitive behavioural therapy (CBT)
o Over 1-2 hours for each weekly session
o Max 4 months of treatment
 Facilitated or non-facilitated self help materials – groups and exercise
 If not effective, add in pharmacotherapy

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

what are the pharmacological therapy options of panic disorder?

A
  • Selective Serotonin Reuptake Inhibitor (SSRI) first line – any licensed for panic disorder
  • Second line – use imipramine or clomipramine
  • If treatment successfully used for 6 months dose can be tapered and stopped
  • DO NOT use benzodiazepines (BZDs), antipsychotics, sedating antihistamines
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

what are considerations you need to take into account with antidepressants?

A
  • may take up to 2 weeks to work
  • there are side effects which you need to warn patient
  • may be a period where they make the depression / anxiety worse
  • need to review within a week of starting
  • doses tend to be much lower for anxiety then for depression
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

what is a major DDI with anti depressants?

A

fluvoxamine and warfarin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

which are short acting benxos?

A

lorazepam, oxazepam

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

what are the long acting benzos?

A

diazepam, clonazepam

17
Q

when would you use a benzo?

A

GAD

do not use for panic disorder or social anxiety

18
Q

what might effect plasma levels of benzos?

A

CYP3A3/4 enzume inducers

19
Q

what are the side effects of benzos?

A

sedation, falls, confusion, amnesia, aggression, disinhibition, tolerance and dependence

20
Q

what might long term treatment of benzos result in?

A

tolerance - within 3-14 days
physical dependence
withdrawal reactions

21
Q

what do you do to avoid withdrawal?

A

you need to come of them very slowly and titrate the dose down
• Successful withdrawal from treatment may take months, especially for long term users
• Switch patients on short/intermediate acting treatments to diazepam (useful liquid preparation)
• Reduce dose gradually as abrupt withdrawal can be dangerous, e.g. 10% every 2 weeks
• Slow withdrawal does not eliminate ADRs – psychological therapy may help
• When withdrawal symptoms emerge, slow/halt titration, slight dose increase may be necessary