ANXIETY Flashcards

1
Q

performance anxiety relationship

A

yerkes-dodson law

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2
Q

The interalated components of anxiety

A
  1. thoughts of having apprehensive, nervouse or frightened

2. the awareness of a physical reactio to anxiery (autonomic or peripheral anxiety)

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3
Q

anxiety patterns of pathology

A
1 Generalised (free floating) anxiery - mild/moderate lasting hours days around normal life events
2 Paroxysmal anxiety- abrupt onset and stron autonomic sx - can be on background of GAD but phobias most common
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4
Q

Physical sx of anxiety

A
  • tachycardia
  • palpitations
  • htn
  • sob
  • chest pain/discomfort
  • choking sensation
  • tremors/shaking
  • muscle tension
  • dry mouth
  • sweating
  • cold/skin
  • N&V
  • Diarrhoea
  • abdominal discomfort
  • dizziness/syncope
  • mydrias
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5
Q

Anxiety hx

A
  • onset
  • severity
  • duration (general or paroxysmal)
  • to specific threat or spontaneously?
  • only in context of pre-existing medical or mental health condition
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6
Q

DDX

A

Anxiety diorders
-phobic disorders (agoraphobia, social phobia, specific phobia)

Non situational anxiery disorder

  • GAD
  • Panic Disorder

Reaction to stess or OCD

Other psychiatric conditions
-65% of patients with anxiett gave deppressive sx

anxiety secondary to general medical conditon or psychiatricx substance

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7
Q

Phobic disorders

A

agoraphobia
-crowded spaces - particularly if cannot escape in context of panic disorder

Social phobia
-fear of scrutiny in general but can be specific (e.g public speaking)

Specific phobia

  • situational (flying, elevators)
  • natural environmental (heights, storms, water)
  • blood injection/injury: seeing blood or injury (bradycardia!)
  • animal
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8
Q

GAD ICD-10

A

excessive worry on minor matters and apprehensive most days for 6/12

1) apprehension
2) motor tension (restless, fidgetting, tension headaches, inability to relax)
3) autonomic overactivity

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9
Q

Panic disorder

A

NOT restricted to situation or object

- anticipatory anxiety is anxiety about having panic attacks and can lead to agoraphobia

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10
Q

other psychiatric conditions

A

cause second anxiety with focus in (brackets)

  • eating disorder (gaining weight)
  • somatisization disorder (having many physical complaints)
  • hypochondriacal disorder (having serious illness)
  • delusional beliefs in paranoid schizophrenia (fear of being poisened or killed)
  • deppression (gait or worthlessness)
  • OCD (when having obsessional thought and resisting compulsion)
  • personality disorder (seperation or abandoment, or being rejected or inadequated
  • ADHD (restless and unable to concentrate
  • autism spectrum disorder (unable to understand others)
  • delirium/dementia (not understanding what is going on)
  • anxiery and depression closly related
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11
Q

anxiety medical conditions

A

causing dyspnoea

  • CCF
  • PE
  • COPD
  • pulmonary disease
  • asthma

causing increased sympatheitc outflow

  • hypoglycaemia
  • phaeochromocytoima

causing pain
-malignancies

Other

  • cerebral trauma
  • cushings disease
  • hyperthyroidism
  • temporal lobe epilepsyt
  • vitamin deficiencies
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12
Q

substances

A

intoxications

  • alcohol
  • amphetamines
  • caffeine
  • cannabis
  • cocaine
  • hallucinogens
  • inhalants
  • ketamine
  • NPS
  • phencyclidine

withdrawal

  • alcohol
  • benzodiazepams
  • caffeine
  • cocaine
  • Gamma-hydroxybutyrate/ gamma-butyrolactone
  • nicotine
  • other sedatives and hypnotics
  • opiates

SE of prescribed

  • ADDs (SSRIs in first 2 weeks and rapid discontinuation particularly of paroxetine or venlafaxine)
  • corticosteroids
  • sympathomimetics
  • Thyroid hormones
  • compound analgesics
  • containing caffeine
  • anticholinergics
  • antipsychotics (akathisia)
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13
Q

anxiety hx questions

A
  • do you sometimes wake up feeling anxiousand dreading the day (any form of anxiety)
  • do you worry excessivly about minor matters on most days of the week? (generalised)
  • have you ever been so frightened that your heart was pounding and you thought you might die? (panic attack)
  • do you avoid leaving the house alone becuase you are afraid of having a panic attack or being in situations (like crowded shop/train) from which escape would be difficult/embarrassing? (agoraphobia)
  • do you get anxious in social situations like speaking in front of people (social phobia)
  • do some things or situations make you scared? . . . . do you avoid them? (specific phobia)
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14
Q

epidemiology

A
overall anxiety 12-17% 1 year prevelence
prevelence % and f:m
GAD = 3% AND 2-3:1
pANIC DISORDER = 4% AND 2-3:1
social phobia = 4% and 1:1
specific phobia = 4% and 2:1
PTSD =4% and2:1
OCD = 2% and 1:1

onset most is childhood/adolescence with panic disorder and bit later and ptsd anytime
generally more wommen except social and OCD whcih is equal

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15
Q

aetiology

A

30-50% heritability with considerable genetic overlap with anxiety
panic disorder and ocd most heritable
-GABA, serotonin and NA most associated
-OCD with caudate nucleus damage
-amygdala hyperactivation in PTSD and other anxiety

  • significant traumatic life event needed for PTSD but only 10-30% will develop
  • CBT suggests thuought patterns (innapropriate) lead to overestimation of dangers
  • pavlovian relationship with some phobias eg car crash
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16
Q

Thought process when approaching anxiety

A

anxiety or low mood?
is it substances?
secondary to depression?
other? . . identify subtype and severity:
-mild-moderate (minimal functional impairment)
-moderate - severe = mild marked functional impairment

17
Q

Mild moderate Tx

A

GAD - self help
Panic Disorder - self help
Social phobia - self help
OCD - self help or CBT (Individual or group)
PTSD - <4 watchfull waiting and then trauma focussed CBT
Specific Phobia - self help

18
Q

Moderate-severe tx

A

GAD

  • CBT/ Applied relaxation
  • SSRI (2nd line SSRI /venlafaxine/ pregabalin)

Panic disorder

  • CBT
  • SSRI (2nd line imipramine)

Social Phobia

  • CBT
  • SSRI/prn Propanalol (2nd line MAOI and short benzo)

OCD

  • Individual CBT with ERP (exposure and response prevention therapy - exposure to fear and resist compulsion . .. . gold standard)
  • SSRI (2nd line alt SSRI/ clomipramine)

PTSD

  • trama focused CBT/ emdr
  • PAROXETINE/MIRTAZOPINE (2ND LINE TCA) + z drub/bezo 4 sleep

Specific Phobia

  • CBT
  • prn benzo insituations
19
Q

psychosocial tx

A

CBT great for most anxiety

  • secific phobias = desensitisation, flooding and remodelling CBT
  • Panic disorder = slow cycle and how it works and then challenge it
  • PTSD = trauma focussed CBT or eye movement desensitising and reprocessing (think about trauma with other stimulus)
  • applied relaxtion in GAD (muscle thing)
  • counselling for stressful life events
20
Q

phaemacological tx

A
  • SSRIs, venlafaxine and TCAs take longer to work and may have initial anxiety
  • benzos more PTSD or frequent PRN
  • pregabalin 2nd line GAD
  • clomiparamine more for OCD as SEROTONIN HEAVY
  • BETA BLOCKER FOR AUTONOMIC AROUSAL
21
Q

Prognosis

A

GAD - likely to be chronic and fluctuating

  • Panic D - 1/2 free after 3 years but 1/3 will have chronic life affecting . . .. common to have agoraphobia after 1 year
  • social phobia - chronic course fluctiating with life stress
  • specific phobias - chronic esp if developed in childhood
  • PTSD - 1/2 recover in 3 months, 1/3 will have mod-sever long term dependent on severity, proximity and duration of trauma
  • OCD - chronic fluctuatinng with stress and 15% chronic deteriation
22
Q

Obsessions definition

A

involuntary thoughts, images or impulses that are:

1) recurrent and intrusive and are experience as unpleasant or distressing
2) enter mind against conscious resistance
3) recognise as produce of own mind (pt often has good insight)

23
Q

compulsions definition

A

repetitive mental (eg matra/counting) or physical (checking, handwashing, reassuring) acts that

1) pts feel compelled to do
2) performed to reduce anxiety (even though actions unrelated or exagerated excessivly)

24
Q

Examples of reslated O and Cs

A
  • fear of contamination leading to excessive washing
  • pathological doubt leading to exhaustive checking
  • violent/reprimandable thoughts leading to redemption act/ reassurance
  • need for symetry/precison leading to repeatedly rearranging objects
25
Q

OCD ICD-10

A
  • must be present > 2 weeks and are a source of distress or interfering with pt functioning
  • aknowledged as coming from own mind
  • Os unpleasantly repetitive
  • at least one thought/act resisted unsuccessfully
  • Compulsion not in itself pleasurable (excluding relief of anxiety)
26
Q

OCD DDx

A
  • eating disorders (don’t think actions excessive)
  • Anakastic PD - not true OCs
  • Autism - pleasurable repetition and not resisted
  • Hypochondrial disorder
  • Schizophrenia - not own thoughts
  • Deppression - whcih came firstOC sx often resolve with tx
27
Q

OCD thinking process

A

OC sx for more than 2 weeks?

Pt meet criteria for other diagnosis?- no? . . . then diagnose OCD

OCs only about other dx? -yes? Then diagnose that condition only
No? - then diagnose OCD and other conditon