Antivirals

Question 1

Treatment of hepatitis B involves antivirals which target ___, while treatment of hepatitis C involves antivirals which target ___.

Answer 1

Treatment of hepatitis B involves antivirals which target reverse transcriptase, while treatment of hepatitis C involves antivirals which target RNA-dependent RNA polymerase, HCV protease, and NS5A.

Question 2

Ledipasvir

Answer 2

Antiviral for hepatitis C

Targets the protein NS5A, a protein crucial for hepatitis C virion assembly

Question 3

Sofosbuvir

Answer 3

Antiviral for hepatitis C

Inhibits NS5B, hepatitis C’s RNA-dependent RNA polymerase