Antivirals Flashcards

1
Q

What is the brand name for tenofovir?

A

Viread

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2
Q

What is the ADR for tenofovir?

A

Renal insufficiency

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3
Q

What is a special consideration for tenofovir?

A

Use with emtricitabine for PrEP and PEP

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4
Q

What is the trade name for Viread?

A

Tenofovir Disoproxil Fumate

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5
Q

What is the brand name for Emtriciabine?

A

Emtriva

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6
Q

What is the trade name for Emtriva?

A

Emtricitabine

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7
Q

What is an ADR of Emtricitabine?

A

Hyperpigmentation of the palms and skin

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8
Q

What is the trade name for Retrovir?

A

Zidovudine

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9
Q

What is the brand name for Zidovudine?

A

Retrovir

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10
Q

What is an ADR of Zidovudine?

A

Bone marrow suppression

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11
Q

What is the brand name of Lamivudine?

A

Epivir

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12
Q

What is the trade name Epivir?

A

Lamivudine

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13
Q

What is a special consideration for Lamivudine?

A

Can build resistance if used to treat HBV (Hep B)

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14
Q

What is the combination of emtricitabine and tenofovir called?

A

Truvada

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15
Q

What are the components of Truvada?

A

Emtricitabine and tenofovir

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16
Q

What is the combination of Emtricitabine and tenofovir and efavirenz called?

A

Atripla

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17
Q

What are the components of Atripla?

A

Emtricitabine and tenofovir and efavirenz

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18
Q

What are the components of Stribild?

A

Emtricitabine and tenofovir and elvitegravir and cobiscat

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19
Q

What is the combination of emtricitabine and tenofovir and elvitegravir and cobiscat called?

A

Stribild

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20
Q

What are the components of Triumeq?

A

Abacavir and lamivudine and dolutegravir

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21
Q

What is the combination of Abacavir and Lamivudine and Dolutegravir called?

A

Triumeq

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22
Q

What is the trade name of Sustiva?

A

Efaviranz

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23
Q

What is the brand name of Efaviranz?

A

Sustiva

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24
Q

What are the ADR of Efavirance?

A

CNS effects
Rash
Increased LFTs
False + for cannabis

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25
Q

What is a special consideration of Efaviranz?

A

Take on an empty stomach

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26
Q

What is the trade name of Edurant?

A

Rilpivirine

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27
Q

What is the brand name of Rilpivirine?

A

Edurant

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28
Q

What is a dosing consideration for Rilpivirine?

A

Not for use in high viral loads

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29
Q

What DI should one be aware of with Rilpivirine?

A

PPIs

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30
Q

What is the trade name for Viramune?

A

Nevirapine

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31
Q

What is the brand name for Nevirapine?

A

Viramune

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32
Q

What is and ADR of Nevirapine?

A

Hepatitis

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33
Q

What is Ritonavir aka?

A

Norvir

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34
Q

What is Norvir aka?

A

Ritonavir

35
Q

What is Atazanavir aka?

A

Reyataz

36
Q

What is Reyataz aka?

A

Atazanavir

37
Q

What is Darunavir aka?

A

Prezista

38
Q

What is Prezista aka?

A

Darunavir

39
Q

What is Lopinavir/ritonavir aka?

A

Kaletra

40
Q

What is Kaletra aka?

A

Lovinavir/ritonavir

41
Q

What is a dosing consideration of Ritonavir?

A

Never a monotherapy

42
Q

What is a consideration of all PIs?

A

Hepatotoxicity

43
Q

What is a DI of Atazanavir?

A

PPIs

44
Q

What is an ADR of Atazanavir?

A

Indirect hyperbilirubinemia

45
Q

What is an ADR for Darunavir?

A

Rash

Hepatotoxicity

46
Q

What is a DI of Darunavir?

A

Sulfa allergic pts

47
Q

What is a special consideration of Lopinavir/ritonavir?

A

Drug of choice in pregnancy

48
Q

What is Raltegravir aka?

A

Isentress

49
Q

What is Isentress aka?

A

Raltegravir

50
Q

What is Dolutegravir aka?

A

Tivicay

51
Q

What is Tivicay aka?

A

Dolutegravir

52
Q

What is an ADR of Raltegravir?

A

Increased CK

53
Q

What is an ADR of Stribild?

A

Increased CK

54
Q

What is an ADR of Dolutegravir?

A

Increased CK

55
Q

What is Acyclovir aka?

A

Zovirax

56
Q

What is Zovirax aka?

A

Acyclovir

57
Q

What is Valacyclovir aka?

A

Valtrex

58
Q

What is Valtrex aka?

A

Valacyclovir

59
Q

What is Famciclovir aka?

A

Famvir

60
Q

What is Famvir aka?

A

Famciclovir

61
Q

What is a special consideration of Valganciclovir?

A

Drug of choice for CMV Retinitis

62
Q

What is an ADR of Ganciclovir?

A

Bone marrow toxicity

63
Q

What is Ganciclovir used to treat?

A

CMV

64
Q

What is Valganciclovir used to treat?

A

CMV

65
Q

What is Foscarnet used to treat?

A

CMV

66
Q

What is Acyclovir used to treat?

A

HSV and VZV

67
Q

What is Valacyclovir used to treat?

A

HSV and VZV

68
Q

What is Famiclovir used to treat?

A

HSV and VZV

69
Q

What is an ADR of Foscarnet?

A

Nephrotoxicity

70
Q

What is a dosing consideration for valganciclovir?

A

PO only

71
Q

What does Tenofovir treat?

A

HIV and HBV

72
Q

What does Entecavir treat?

A

HIV

73
Q

What does Lamivudine treat?

A

HIV and HBV

74
Q

What is the ADR of Enecavir?

A

Dizziness

Fatigue

75
Q

What are CIs for Interferon use?

A

AI dz
Arrhthmia
Pregnancy
Hepatic decompensation

76
Q

What are ADRs of Interferon?

A

Flu like symptoms

77
Q

What does Sofosbuvir treat?

A

Hep C

78
Q

What does Harvoni treat?

A

Hep C

79
Q

What DI does Harvoni have?

A

PPI

80
Q

What does Amantadine treat?

A

Influenza A

81
Q

What does Rimantadine treat?

A

Influenza A

82
Q

What does Oseltamivir treat?

A

Influenza A & B

83
Q

What does Zanamivir treat?

A

Influenza A & B

84
Q

What considerations does Zanamivir have?

A

Avoid in pts with Asthma and COPD