Antivirals Flashcards
What is the brand name for tenofovir?
Viread
What is the ADR for tenofovir?
Renal insufficiency
What is a special consideration for tenofovir?
Use with emtricitabine for PrEP and PEP
What is the trade name for Viread?
Tenofovir Disoproxil Fumate
What is the brand name for Emtriciabine?
Emtriva
What is the trade name for Emtriva?
Emtricitabine
What is an ADR of Emtricitabine?
Hyperpigmentation of the palms and skin
What is the trade name for Retrovir?
Zidovudine
What is the brand name for Zidovudine?
Retrovir
What is an ADR of Zidovudine?
Bone marrow suppression
What is the brand name of Lamivudine?
Epivir
What is the trade name Epivir?
Lamivudine
What is a special consideration for Lamivudine?
Can build resistance if used to treat HBV (Hep B)
What is the combination of emtricitabine and tenofovir called?
Truvada
What are the components of Truvada?
Emtricitabine and tenofovir
What is the combination of Emtricitabine and tenofovir and efavirenz called?
Atripla
What are the components of Atripla?
Emtricitabine and tenofovir and efavirenz
What are the components of Stribild?
Emtricitabine and tenofovir and elvitegravir and cobiscat
What is the combination of emtricitabine and tenofovir and elvitegravir and cobiscat called?
Stribild
What are the components of Triumeq?
Abacavir and lamivudine and dolutegravir
What is the combination of Abacavir and Lamivudine and Dolutegravir called?
Triumeq
What is the trade name of Sustiva?
Efaviranz
What is the brand name of Efaviranz?
Sustiva
What are the ADR of Efavirance?
CNS effects
Rash
Increased LFTs
False + for cannabis
What is a special consideration of Efaviranz?
Take on an empty stomach
What is the trade name of Edurant?
Rilpivirine
What is the brand name of Rilpivirine?
Edurant
What is a dosing consideration for Rilpivirine?
Not for use in high viral loads
What DI should one be aware of with Rilpivirine?
PPIs
What is the trade name for Viramune?
Nevirapine
What is the brand name for Nevirapine?
Viramune
What is and ADR of Nevirapine?
Hepatitis
What is Ritonavir aka?
Norvir
What is Norvir aka?
Ritonavir
What is Atazanavir aka?
Reyataz
What is Reyataz aka?
Atazanavir
What is Darunavir aka?
Prezista
What is Prezista aka?
Darunavir
What is Lopinavir/ritonavir aka?
Kaletra
What is Kaletra aka?
Lovinavir/ritonavir
What is a dosing consideration of Ritonavir?
Never a monotherapy
What is a consideration of all PIs?
Hepatotoxicity
What is a DI of Atazanavir?
PPIs
What is an ADR of Atazanavir?
Indirect hyperbilirubinemia
What is an ADR for Darunavir?
Rash
Hepatotoxicity
What is a DI of Darunavir?
Sulfa allergic pts
What is a special consideration of Lopinavir/ritonavir?
Drug of choice in pregnancy
What is Raltegravir aka?
Isentress
What is Isentress aka?
Raltegravir
What is Dolutegravir aka?
Tivicay
What is Tivicay aka?
Dolutegravir
What is an ADR of Raltegravir?
Increased CK
What is an ADR of Stribild?
Increased CK
What is an ADR of Dolutegravir?
Increased CK
What is Acyclovir aka?
Zovirax
What is Zovirax aka?
Acyclovir
What is Valacyclovir aka?
Valtrex
What is Valtrex aka?
Valacyclovir
What is Famciclovir aka?
Famvir
What is Famvir aka?
Famciclovir
What is a special consideration of Valganciclovir?
Drug of choice for CMV Retinitis
What is an ADR of Ganciclovir?
Bone marrow toxicity
What is Ganciclovir used to treat?
CMV
What is Valganciclovir used to treat?
CMV
What is Foscarnet used to treat?
CMV
What is Acyclovir used to treat?
HSV and VZV
What is Valacyclovir used to treat?
HSV and VZV
What is Famiclovir used to treat?
HSV and VZV
What is an ADR of Foscarnet?
Nephrotoxicity
What is a dosing consideration for valganciclovir?
PO only
What does Tenofovir treat?
HIV and HBV
What does Entecavir treat?
HIV
What does Lamivudine treat?
HIV and HBV
What is the ADR of Enecavir?
Dizziness
Fatigue
What are CIs for Interferon use?
AI dz
Arrhthmia
Pregnancy
Hepatic decompensation
What are ADRs of Interferon?
Flu like symptoms
What does Sofosbuvir treat?
Hep C
What does Harvoni treat?
Hep C
What DI does Harvoni have?
PPI
What does Amantadine treat?
Influenza A
What does Rimantadine treat?
Influenza A
What does Oseltamivir treat?
Influenza A & B
What does Zanamivir treat?
Influenza A & B
What considerations does Zanamivir have?
Avoid in pts with Asthma and COPD