Antivirals Flashcards

1
Q

What is the brand name for tenofovir?

A

Viread

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2
Q

What is the ADR for tenofovir?

A

Renal insufficiency

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3
Q

What is a special consideration for tenofovir?

A

Use with emtricitabine for PrEP and PEP

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4
Q

What is the trade name for Viread?

A

Tenofovir Disoproxil Fumate

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5
Q

What is the brand name for Emtriciabine?

A

Emtriva

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6
Q

What is the trade name for Emtriva?

A

Emtricitabine

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7
Q

What is an ADR of Emtricitabine?

A

Hyperpigmentation of the palms and skin

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8
Q

What is the trade name for Retrovir?

A

Zidovudine

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9
Q

What is the brand name for Zidovudine?

A

Retrovir

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10
Q

What is an ADR of Zidovudine?

A

Bone marrow suppression

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11
Q

What is the brand name of Lamivudine?

A

Epivir

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12
Q

What is the trade name Epivir?

A

Lamivudine

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13
Q

What is a special consideration for Lamivudine?

A

Can build resistance if used to treat HBV (Hep B)

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14
Q

What is the combination of emtricitabine and tenofovir called?

A

Truvada

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15
Q

What are the components of Truvada?

A

Emtricitabine and tenofovir

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16
Q

What is the combination of Emtricitabine and tenofovir and efavirenz called?

A

Atripla

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17
Q

What are the components of Atripla?

A

Emtricitabine and tenofovir and efavirenz

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18
Q

What are the components of Stribild?

A

Emtricitabine and tenofovir and elvitegravir and cobiscat

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19
Q

What is the combination of emtricitabine and tenofovir and elvitegravir and cobiscat called?

A

Stribild

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20
Q

What are the components of Triumeq?

A

Abacavir and lamivudine and dolutegravir

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21
Q

What is the combination of Abacavir and Lamivudine and Dolutegravir called?

A

Triumeq

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22
Q

What is the trade name of Sustiva?

A

Efaviranz

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23
Q

What is the brand name of Efaviranz?

A

Sustiva

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24
Q

What are the ADR of Efavirance?

A

CNS effects
Rash
Increased LFTs
False + for cannabis

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25
What is a special consideration of Efaviranz?
Take on an empty stomach
26
What is the trade name of Edurant?
Rilpivirine
27
What is the brand name of Rilpivirine?
Edurant
28
What is a dosing consideration for Rilpivirine?
Not for use in high viral loads
29
What DI should one be aware of with Rilpivirine?
PPIs
30
What is the trade name for Viramune?
Nevirapine
31
What is the brand name for Nevirapine?
Viramune
32
What is and ADR of Nevirapine?
Hepatitis
33
What is Ritonavir aka?
Norvir
34
What is Norvir aka?
Ritonavir
35
What is Atazanavir aka?
Reyataz
36
What is Reyataz aka?
Atazanavir
37
What is Darunavir aka?
Prezista
38
What is Prezista aka?
Darunavir
39
What is Lopinavir/ritonavir aka?
Kaletra
40
What is Kaletra aka?
Lovinavir/ritonavir
41
What is a dosing consideration of Ritonavir?
Never a monotherapy
42
What is a consideration of all PIs?
Hepatotoxicity
43
What is a DI of Atazanavir?
PPIs
44
What is an ADR of Atazanavir?
Indirect hyperbilirubinemia
45
What is an ADR for Darunavir?
Rash | Hepatotoxicity
46
What is a DI of Darunavir?
Sulfa allergic pts
47
What is a special consideration of Lopinavir/ritonavir?
Drug of choice in pregnancy
48
What is Raltegravir aka?
Isentress
49
What is Isentress aka?
Raltegravir
50
What is Dolutegravir aka?
Tivicay
51
What is Tivicay aka?
Dolutegravir
52
What is an ADR of Raltegravir?
Increased CK
53
What is an ADR of Stribild?
Increased CK
54
What is an ADR of Dolutegravir?
Increased CK
55
What is Acyclovir aka?
Zovirax
56
What is Zovirax aka?
Acyclovir
57
What is Valacyclovir aka?
Valtrex
58
What is Valtrex aka?
Valacyclovir
59
What is Famciclovir aka?
Famvir
60
What is Famvir aka?
Famciclovir
61
What is a special consideration of Valganciclovir?
Drug of choice for CMV Retinitis
62
What is an ADR of Ganciclovir?
Bone marrow toxicity
63
What is Ganciclovir used to treat?
CMV
64
What is Valganciclovir used to treat?
CMV
65
What is Foscarnet used to treat?
CMV
66
What is Acyclovir used to treat?
HSV and VZV
67
What is Valacyclovir used to treat?
HSV and VZV
68
What is Famiclovir used to treat?
HSV and VZV
69
What is an ADR of Foscarnet?
Nephrotoxicity
70
What is a dosing consideration for valganciclovir?
PO only
71
What does Tenofovir treat?
HIV and HBV
72
What does Entecavir treat?
HIV
73
What does Lamivudine treat?
HIV and HBV
74
What is the ADR of Enecavir?
Dizziness | Fatigue
75
What are CIs for Interferon use?
AI dz Arrhthmia Pregnancy Hepatic decompensation
76
What are ADRs of Interferon?
Flu like symptoms
77
What does Sofosbuvir treat?
Hep C
78
What does Harvoni treat?
Hep C
79
What DI does Harvoni have?
PPI
80
What does Amantadine treat?
Influenza A
81
What does Rimantadine treat?
Influenza A
82
What does Oseltamivir treat?
Influenza A & B
83
What does Zanamivir treat?
Influenza A & B
84
What considerations does Zanamivir have?
Avoid in pts with Asthma and COPD