Antivirals Flashcards
1
Q
What must antiviral agents do to work
A
Either block entry into or out of cell or be active inside the host cell
2
Q
When are antivirals most active
A
When the virus is replicating
3
Q
3 classes of how antivirals work
A
- DNA polymerase inhibitors
- Protease inhibitors
- Reverse transcriptase inhibiors
4
Q
What class is Acyclovir
A
DNA polymerase inhibitors
5
Q
What class is Nelfinovir and Ritoavir
A
Protease inhibitors
6
Q
What is Highly Antiviral Therapy (HAART)
What 2 antivirals are mostly used
A
Combination therapy with at least 3 drugs
Most used are protease inhibitors and reverse transcriptase (NRTIs)
Produces powerful multifaceted attack, simultaneous blockage of multiple steps essential for viral activity and reproduction
