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Microbiologia- Virus > Antivirales > Flashcards

Antivirales Flashcards

1
Q

Herpes Simplex

A

Aciclovir

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2
Q

Virus de Varicela

A

Aciclovir

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3
Q

Citomegalovirus

A

Ganciclovir

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4
Q

Nivel al que actua el aciclovir y el ganciclovir

A

sobre la polimerasa viral

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5
Q

Principales anti-retrovirales

A 
inhibidores de la transcriptasa inversa 
inhibidores de proteasa 
inhibidores de fusion 
inhibidores de integrasa 
antagonistas de CCR5
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6
Q

Principales antivirales contra influenza

A

adamantanos

inhibidores de neuraminidasa

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7
Q

Principales inhibidores de neuraminidasa

A

oseltamivir

zanamivir

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8
Q

Hepatitis B

A

interferon
interferon- pegilado
analogos de nucleotidos/nucleosidos

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9
Q

principal mecanicanismo que genera resistencia en VHS

A

mutaciones en el gen que codifica para la timidina kinasa

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10
Q

Receptor para Influenza

A

Acido sálico- Gucoproteina

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11
Q

Receptor para Adenovirus

A

integrinas unión a matriz extracelular

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12
Q

Receptor para Epstein Barr

A

CR2 (CD21) – Receptor de reconocimiento

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13
Q

Receptor para Hepatitis A

A

2 macroglobulina – Proteina plasmática inhibidora de la coagulación

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14
Q

Receptor para Herpes simple

A

Heparán sulfato - glucoproteína

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15
Q

Receptor para VIH

A

CD4, CXCR4, CCR5 Correceptor, receptores de quimiocinas

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16
Q

Receptor para Sarampión

A

CD46 – Regulación del complemento

Rabia - Receptor de acetilcolina – Señalización

17
Q

Receptor para Rotavirus

A

Integrinas a2p1 y a4p1 – Receptores para la matriz extracelular.

18
Q

Queratoconjuntivitis

A

vidarabina

19
Q

Herpes genital

A

valaciclovir

20
Q

son los analogos de nucleosidos en el tratamiento del herpes virus

A

acicovir
valaciclovir
ganciclovir
penciclovir

21
Q

son los derivados aciclicos en el tratamiento del herpes virus

A

cidofovir

22
Q

son los analogos de pirofosfato en el tratamiento del herpes virus

A

foscarnet

23
Q

citomegalovirus

A

valaganciclovir

24
Q

Varicela

A

aciclovir

25
Q

Aciclovir es activado

A

timidin kinasa viral, el cual lo fosforila y asi inhibe la polimerasa viral

26
Q

Antiviral que puede cubrir la resistencia a aciclovir

A

cidofovir ya que no necesita ser fosforilado

27
Q

son antivirales usados como tratamiento en el herpes que no requieren de activacion

A

cidofovir

foscarnet

28
Q

efectos adversos del foscarnet

A

toxicidad renal
alteraciones electroliticas
alteraciones en el SNC
fiebre

29
Q

HAART

A

Tratamiento antirretroviral altamente activo

2 inhibidores de transcriptasa inversa + inhibidor de proteasa

30
Q

Hepatitis C

A

Daclatasvir (Daldinza)

31
Q

Antivirales que rienen resistencia contra influenza A

A

Amantadina. Antiflu-Des.

Rimantadina. Gabiron

Microbiologia- Virus (20 decks)

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