Antiviral drugs Flashcards
0
Q
Acyclovir?
A
Inhibitor of replication.
Competitive inhibitor of DNA polymerase with selective toxicity - only activated in infected cells by thymidine kinase.
1
Q
Amantadine?
A
Inhibitor of uncoating.
2
Q
Oseltamivir?
A
Inhibits budding of flu virus by inhibiting neuraminidase (enzyme which breaks bonds between viral coat and cell membrane).
3
Q
Maraviroc?
A
CCR5 antagonist.
4
Q
Enfluvirtide?
A
Fusion inhibitor
5
Q
Zidovudine?
A
Reverse transcriptase inhibitor.
Nucleoside analogue, reverse transcriptase inhibitor (NRTI)
Thymidine analogue.
Competitive inhibitor.
6
Q
Nevirapine
A
Reverse transcriptase inhibitor - non nucleoside. (NNRTI).
Non competitive inhibitor - allosteric inhibitor.
7
Q
Raltegravir
A
Integrate inhibitor
8
Q
Saquinavir?
A
Protease inhibitor.
