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Antivirals > Antiviral Drugs > Flashcards

Antiviral Drugs Flashcards

1
Q

Drugs for Herpes Virus

A

Acyclovir, Valacyclovir, Penciclovir, Famciclovir

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2
Q

Drugs for CMV

A

Ganciclovir and Valganciclovir

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3
Q

Drugs Active against HSV and/or CMV

A

Cidofovir and Foscarnet

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4
Q

ART: Entry (CCR5) Inhibitors

A

Maraviroc (Selzentry)

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5
Q

ART: Fusion Inhibitors

A

Enfuvirtide (T-20, Fuzeon)

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6
Q

ART: Nucleoside RT Inhibitors (NRTIs)

A

Zidovudine, Abacavir, Stavudine, Didanosine

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7
Q

ART: Nucleotide RT Inhibitors

A

Tenofovir

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8
Q

Retrovir

A

Zidovudine (aka, AZT, azidothymidine, ZDV - GSK, 1987

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9
Q

Videx

A

didanosine, ddI, dideoxyinosine - BMS, 1991

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10
Q

Zerit

A

stavudine, d4T - BMS, 1994

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11
Q

Epivir

A

lamivudine, 3TC - GSK, 1995

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12
Q

Combivir

A

lamivudine and zidovudine - GSK, 1995

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13
Q

Ziagen

A

abacavir - GSK, 1997

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14
Q

Videx EC

A

enteric coated didanosine - BMS, 2000

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15
Q

Trizivir

A

abacavir, zidovudine, lamivudine - GSK, 2000

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16
Q

Viread

A

tenofovir disoproxil fumarate, Gilead, 2001

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17
Q

Emtriva

A

FTC, emtricitabine - Gilead Sciences, 2003

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18
Q

Truvada

A

tenofovir disoproxil/emtricitabine - Gilead Sciences, Inc. 2004

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19
Q

Epzicom

A

abacavir/lamivudine - GSK, 2004

20
Q

Nonnucleoside Reverse Transcriptase Inhibitors (NNRTIs)

A

Brand Names: Viramune, Rescriptor, Sustiva, Atripla, Intelence, Edurant, Complera

21
Q

NNRTI: Viramune

A

nevirapine, BI-RG-587, 1996

22
Q

NNRTI: Rescriptor

A

delaviridine, DLV, 1997

23
Q

NNRTI: Sustiva

A

efavirenz, 1998

24
Q

NNRTI: Atripla

A

efavirenz, emtricitabine, tenofovir, 2006

25
Q

NNRTI: Intelence

A

etravirine, 2008

26
Q

NNRTI: Edurant

A

rilpivirine, 2011

27
Q

NNRTI: Complera

A

rilpivirine, emtricitabine, tenofovir, 2011

28
Q

Integrase Inhibitors

A

Raltegravir (Isentress), Elvitegravir

29
Q

Isentress

A

raltegravir, Marck 2008, integrase inhibitor

30
Q

Stribild

A

elvitegravir, cobicistat, tenofovir, emtricitabine, Gilead 2012, integrase inhibitor

31
Q

dolutegravir

A

integrase inhibitor, Gilead - sumbitted to FDA in 2013

32
Q

Protease Inhibitors

A

Invirase, Crixivan, Norvir, Viracept, Fortovase, Agenerase, Kaletra, Lexiva, Reyataz, Aptivus, Prezista

33
Q

Invirase

A

PI, saquinavir mesylate, SQV 1995

34
Q

Crixivan

A

PI, indinavir 1996

35
Q

Norvir

A

PI, ritonavir, ABT-538 1996

36
Q

Viracept

A

PI, nelfinavir mesylate, NFV 1997

37
Q

Fortovase

A

PI, saquinavir 1997

38
Q

Agenerase

A

PI, amprenavir 1999

39
Q

Kaletra

A

PI, lopinavir and ritonavir 2000

40
Q

Lexiva

A

PI, fosamprenavir calcium 2003

41
Q

Reyataz

A

PI, atazanavir sulfate 2003

42
Q

Aptivus

A

PI, tipranavir 2005

43
Q

Prezista

A

PI, darunavir 2006

44
Q

Drugs to suppress viral replication of HepB

A

NNRTIs: Lamivudine (Epivir), Adefovir (Hepsera), Entecavir (Baraclude), Telbivudine (Tyzeka), Tenofovir (Viread)D

45
Q

Drugs that modulate immune response

A

Interferons; classes: alpha-2b –> for treatments of acute and chronic hepatitis C/ alpha-2a —> for treatment of chronic HepC

46
Q

Drugs to suppress viral replication of HepC

A

Telaprevir/Boceprevir, Ribavirin

47
Q

Anti-influenza agents

A

Amantadine, Rimantadine, Zanamivir (Relenza), Oseltamivir (Tamiflu)

Antivirals (1 decks)

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