Antituberculous drugs Flashcards
1
Q
RESPIre
A
Rifampin Ethambutol Streptomycin Pyrazinamide Isoniazid
2
Q
MOR of Isoniazid
A
Delete the catalase gene so pro INH cannot be converted to active INH
3
Q
Precaution while using Isoniazid
A
Vitamin B6 supplements to reduce risks of neurotoxicity
4
Q
MOA of Rifampin
A
Inhibits DNA dependent RNA polymerase.
5
Q
What warning will you give a patient you prescribe Rifampicin
A
Red man syndrome ( Reddening of body fluids)
6
Q
Most common side effect of Ethambutol
A
Red green colour blindeness
Avoid in children below 6 years
7
Q
Whats used as Prophylaxis for MAC
A
Azithromycin and clarithromycin
8
Q
Which of the anti TB drugs needs an acidic environment?
A
Pyrazinamide
