ANTITUBERCULAR MEDICATIONS Flashcards

1
Q

What is the generic name of the first-line anti-tuberculosis medication commonly known as Rifampin?

A

Rifampicin

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2
Q

True or False: Isoniazid is used primarily for the treatment of latent tuberculosis infections.

A

True

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3
Q

What is the primary action of Pyrazinamide?

A

To kill Mycobacterium tuberculosis in acidic environments.

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4
Q

Fill in the blank: Ethambutol is primarily used to prevent the development of __________.

A

drug resistance

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5
Q

What are common adverse reactions associated with Isoniazid?

A

Hepatotoxicity, peripheral neuropathy, and hypersensitivity reactions.

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6
Q

Which anti-tuberculosis medication can cause orange-red discoloration of bodily fluids?

A

Rifampin

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7
Q

What nursing intervention is essential when administering Streptomycin?

A

Monitor renal function and hearing.

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8
Q

True or False: Directly Observed Therapy (DOT) is a recommended approach for ensuring adherence to anti-tuberculosis treatment.

A

True

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9
Q

What should be monitored in patients taking Pyrazinamide?

A

Liver function tests.

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10
Q

Which medication is contraindicated in patients with a history of gout?

A

Pyrazinamide

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11
Q

What is the mechanism of action of Ethambutol?

A

Inhibits the synthesis of the mycobacterial cell wall.

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12
Q

Fill in the blank: The standard treatment regimen for drug-susceptible tuberculosis typically lasts for __________ months.

A

6 to 9

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13
Q

Which anti-tuberculosis drug requires careful monitoring due to potential ocular toxicity?

A

Ethambutol

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14
Q

What is the main adverse effect of Rifampin?

A

Hepatotoxicity

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15
Q

True or False: Patients on Isoniazid should be advised to consume alcohol.

A

False

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16
Q

What is the recommended nursing intervention for managing peripheral neuropathy associated with Isoniazid?

A

Supplementation with pyridoxine (Vitamin B6).

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17
Q

Fill in the blank: The primary goal of anti-tuberculosis therapy is to __________.

A

eradicate Mycobacterium tuberculosis

18
Q

Which medication is considered a second-line treatment for tuberculosis?

A

Capreomycin

19
Q

What is the action of Rifapentine?

A

It inhibits bacterial RNA synthesis.

20
Q

True or False: Tuberculosis can be transmitted through casual contact.

21
Q

What is an important nursing intervention for patients receiving multi-drug therapy for tuberculosis?

A

Educate the patient on the importance of medication adherence.

22
Q

Fill in the blank: The BCG vaccine is primarily used for __________ prevention of tuberculosis.

A

prevention

23
Q

What is a common side effect of Streptomycin?

A

Ototoxicity

24
Q

Which anti-tuberculosis medication is known for its potential to cause vision changes?

A

Ethambutol

25
Fill in the blank: A patient on Rifampin should be informed that __________ may occur.
discoloration of urine
26
What is the primary reason for using a combination of anti-tuberculosis medications?
To prevent the development of drug resistance.
27
True or False: Patients should be monitored for liver function while on Isoniazid and Rifampin.
True
28
What should be included in patient education regarding anti-tuberculosis medications?
The importance of completing the full course of treatment.
29
What is the first-line treatment regimen for drug-susceptible tuberculosis?
Isoniazid, Rifampin, Pyrazinamide, and Ethambutol.
30
Fill in the blank: __________ is used to treat drug-resistant tuberculosis.
Second-line agents
31
What is the significance of DOT in tuberculosis treatment?
It ensures that patients take their medications as prescribed.
32
Which anti-tuberculosis medication is contraindicated in pregnancy?
Streptomycin
33
What are the signs of hepatotoxicity to monitor in patients taking anti-tuberculosis medications?
Jaundice, dark urine, and elevated liver enzymes.
34
Fill in the blank: The treatment for latent tuberculosis infection typically involves __________.
Isoniazid alone or Rifampin alone.
35
What is a potential drug interaction to be aware of when prescribing Rifampin?
It can reduce the effectiveness of oral contraceptives.
36
True or False: Ethambutol can cause allergic reactions.
True
37
What is the role of the nurse in managing a patient with tuberculosis?
To provide education, monitor for side effects, and ensure adherence to therapy.
38
What is the preferred route of administration for Streptomycin?
Intramuscular injection
39
Fill in the blank: Patients should be advised to report any __________ while on Isoniazid.
tingling or numbness
40
What is the action of the anti-tuberculosis drug Bedaquiline?
It inhibits mycobacterial ATP synthase.