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Pharm Sci II > Antiseizure Drugs > Flashcards

Antiseizure Drugs Flashcards

1
Q

Carbamazepine Tegretol®

A

Voltage-Gated Sodium Channel Blockers

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2
Q

Clonazepam Klonopin®

A

Benzodiazepine

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3
Q

Diazepam Valium®

A

Benzodiazepine

GABAergic drug

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4
Q

Divalproex Sodium Depakote®

A

Multiple Mechanisms= broad spectrum (Sodium salt dimer of Valproic Acid)

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5
Q

Fosphenytoin Cerebyx®

A

Voltage-Gated Sodium Channel Blockers

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6
Q

Gabapentin Neurontin®

A

Unknown Mechanisms of Action

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7
Q

Lamotrigine Lamictal®

A

Voltage-Gated Sodium Channel Blockers

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8
Q

Levetiracetam Keppra®

A

Unknown Mechanisms of Action

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9
Q

Ezogabine Potiga®

A

Activates inwardly rectifying K+ channels

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10
Q

Lorazepam Ativan®

A

Benzodiazepine

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11
Q

Oxcarbazepine Trileptal®

A

Voltage-Gated Sodium Channel Blockers

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12
Q

Phenobarbital Luminol®

A

Barbiturates (Narrow therapeutic range)

GABAergic drug

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13
Q

Phenytoin Dilantin®

A

Voltage-Gated Sodium Channel Blockers

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14
Q

Pregabalin Lyrica®

A

Voltage-gated calcium channel antagonist in the CNS

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15
Q

Tiagabine Gabitril®

A

GABAergic drug
Blocks the GABA reuptake channel
(narrow spectrum) for partial seizures
“designer drug” for epilepsy

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16
Q

Topiramate Topamax®

A

Multiple Mechanisms= broad spectrum

17
Q

Valproic Acid Depakene®

A

Multiple Mechanisms= broad spectrum

18
Q

Zonisamide Zonegran®

A

Voltage-Gated Sodium Channel Blockers

19
Q

Lacosamide VIPMAT®

A
  • enhances slow-inactivation of Na+ channels= less availability of Na+ channels for depolarization.
  • exact mechanism for this is unknown
  • reduced seizure activity (partial seizures)

Pharm Sci II (19 decks)

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