antipsychotic injectables

Question 1

haloperidol

Answer 1

EPS
given Q4week

Question 2

risperidal consta

Answer 2

rsiperidone LA injection
must supplement with oral for 3 weeks

Question 3

perseris

Answer 3

risperidone SQ abdominal injectio

Question 4

rykindo

Answer 4

risperidone IM injection q2 weeks
oral overlap is 7 days

Question 5

uzedy

Answer 5

risperidone
abdominal or upper arm SQ injection
q2months

Question 6

ivega sustena

Answer 6

paliperidone
loading dose then q4weeks
initial dose better in delt for absorption
renal elimination needs dose adjustment
no need for oral overlap

Question 7

invega trinza

Answer 7

paliperidone
q3months
can be inititated on a patient on stable invega sustenna for 4 doses
recommended delt injection
not recommended if CrCl <50

Question 8

invega hafyera

Answer 8

may be initiated if patient has 4 doses invega sustenna or 1 dose invega trinza
glute only due to size of dose

Question 9

zyprexa relprevv

Answer 9

olanzapine
post pose delirium sedation syndrome
due to olanzapine overdose

Question 10

abilify maintena

Answer 10

delt or glute injection
overlap for 14 days after first injection
dose adjustment required if taking 2D6 or 3A4 inhibitors or 3A4 inducers

Question 11

abilify asimtufii

Answer 11

q 2months dosing
glute only
continue aripiprazole for 2 weeks after first injection

Question 12

aristada

Answer 12

prodrug of aripiprazole
overalp with oral for 3 weeks after first injection

Question 13

aristada initio

Answer 13

avoids the need for 21-day oral overlap of antipyschotic
avoid in patients who are 2D6 poor metabolizers or with strong 3A4 or 2D6 inhibitors

Question 14

olanzapine IR IM

Answer 14

cannot be given with BZD IR injection because of respiratory depression