Antipsychotic drug interactions Flashcards
1
Q
Which drugs given with antipsychotics will lead to increased QT interval?
A
SSRIs, quinolones, amiodarone, quinine, macrolides,
2
Q
Which drugs given with antipsychotics will lead to increased risk of extrapyramidal symptoms ?
A
metoclopramide, Parkinson’s disease, levodopa, dopamine antagonists
3
Q
Which drugs given with antipsychotics will lead to increased risk of CNS depressant effects/ sedation ?
A
hypnotic ( zopiclone), benzos, opioids, anti epileptics
4
Q
Which drugs given with antipsychotics will lead to increased risk of hypotension ?
A
CCB, ACE, ARB, BB, alpha blockers, diuretics, nitrates
5
Q
Which drugs given with antipsychotics will lead to increased risk antimuscarinic side effects ?
A
TCA’s, antihistamines, antimuscarinics ( hyoscine )
