Antiprotozoal Flashcards

1
Q

What drug is for Treatment and chemoprophylaxis of infection with sensitive parasites

A

Chloroquine

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2
Q

What drug under class “Phenanthrene methanol” used to treat P falciparum infections

A

Halofantrine

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3
Q

What drug under class “4-Aminoquinoline” is a treatment of infection with some chloroquine-resistant P falciparum strains and in fixed combinations with artesunate

A

Amodiaquine

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4
Q

What drug under class “Bisquinoline” is used for treatment of P falciparum infection in fixed combination with dihydroaetemisinin

A

Piperaquine

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5
Q

What drug under class “Quinoline methanol” used for intravenous therapy of severe infections with P falciparum

A

Quinidine

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6
Q

What drug under class “quinoline methanol” used for chemoprophylaxis and treatment of infections with P falciparum

A

Mefloquine

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7
Q

What drug under class “8-Aminoquinoline” used for Radical cure and treatment prophylaxis of infections with P vivax and P ovale; alternative chemoprophylaxis for all species

A

Primaquine

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8
Q

What drug under class “Folate antagonist combination” used for treatment of infections with some chloroquine-resistant P falciparum, including combination with artesunate; intermittent preventive therapy in endemic areas

A

Sulfadoxine-pyrimethamine (Fansidar)

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9
Q

What drug under class “Quinone-folate antagonist combination” used for treatment and chemoprophylaxis of P falciparum infection

A

Atovaquone-proguanil (Malarone)

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10
Q

What drug under class “Tetracycline” used for treatment (with quinine) of infections with P falciparum; chemoprophylaxis

A

Doxycycline

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11
Q

What drug under class “Amyl alcohol” used for treatment of P falciparum malaroa in fixed combination with artemether (Coartem)

A

Lumefantrine

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12
Q

What drug under class “Sesquiterpene lactone endoperoxides” used for treatment of P falciparum infections; oral combination therapies for uncomplicated disease; intravenous artesunate for severe disease

A

Artemisinins

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13
Q

Type of regimen that is Co-formulated; first-line therapy in many countries; approved in the USA

A

Artemether-lumefantrine (Coartem, Riamet)

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14
Q

Type of regimen that is Co-formulated; first-line therapy in many African countries

A

Artesunate-amodiaquine (ASAQ, Arsucam, Coarsucam)

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15
Q

Type of regimen that is Co-formulated; first-line therapy in parts of Southeast Asia and South America

A

Artesunate-mefloquine

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16
Q

Type of regimen that is Co-formulated; first-line therapy in some countries in Southeast Asia

A

Dihydroartemisinin-piperaquine (Artekin, Duocotecxin)

17
Q

Type of regimen that is first-line therapy in some countries, but efficacy lower than other regimens in most areas

A

Artesunate-sulfadoxine-pyrimethamine