Antiphospholipid Syndrome, Systemic Scelerosis, Sjogrens

Question 1

Limited Cutaneous Systemic Sclerosis

Answer 1

C – Calcinosis

R – Raynaud’s phenomenon

E – oEsophageal dysmotility

S – Sclerodactyly

T – Telangiectasia

anti-cetromere antibody

Question 2

Diffuse Cutaneous Systemic Sclerosis

Answer 2

CREST +

Cardiovascular problems
Lung problems
Kidney problems

Question 3

What is Antiphospholipid syndrome?

Answer 3

Antiphospholipid antibodies

Blood becomes prone to clotting - hyper-coagulable state

Question 4

Main associations in Antiphospholipid syndrome

Answer 4

Thrombosis

Complications in pregnancy, particularly recurrent miscarriage

Question 5

Antiphospholipid antibodies

Answer 5

Lupus anticoagulant

Anticardiolipin antibodies

Anti-beta-2 glycoprotein I antibodies

Question 6

What is sjogren’s?

Answer 6

autoimmune condition that affects the exocrine glands

Dry mucous membranes - dry mouth, dry eyes and dry vagina

Question 7

Sjogrens antibodies

Answer 7

anti-Ro

anti-La

Question 8

Secondary Sjogren’s

Answer 8

Occurs related to SLE or rheumatoid arthritis

Question 9

Management of Sjogrens

Answer 9

Artificial tears

Artificial saliva

Vaginal lubricants

Hydroxychloroquine is used to halt the progression of the disease

Question 10

Complications in Sjogren’s

Answer 10

Eye infections such as conjunctivitis and corneal ulcers

Oral problems such as dental cavities and candida infections

Vaginal problems such as candidiasis and sexual dysfunction