Antineoplastic Flashcards by Dongca Bawal | Brainscape

Q

Platinum compound MOA

A

DNA Cross links

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Q

Vinca alkaloids MOA

A

Microtubulin inhibition

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Q

Estramustine

A

Tubulin

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Q

taxanes MOA

A

Binds to tubulin subunit –> overly stable microtubules

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Q

Alkylating agents MOA

A

DNA cross linking

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Q

Me hlirethamine

A

DNA crosslinking

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Q

Vinca alkaloids AE

A

Neurotoxicity

SIADH

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Q

Mito,ycin

A

Hemolytic uremic syndrome

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Q

Cyclophosphamide AE

A

Hemorrhagic cystitis

Due to acrolein

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Q

Ifosfamide AE

A

Hemorrhagic cystitis due to acrolein

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Q

StretozotocinAE

A

Nephrotoxicity

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Q

Bleomycin AE

A

Pulmonary fibrosis

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Q

Dactnomycin MOA

A

Intercalation

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