Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

antimicrobial > antimycobacterial drugs > Flashcards

antimycobacterial drugs Flashcards

1
Q

which drug gives the metabolite quinone

A

rifampin (the metabolite is active)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

tuberculosis treatment

A

2HRZE/4HR

Ethamubtol can be replaced with streptomycin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

what can we use isonizaid to treat

A

latent TB infection —> Bacteriostatic (monotherpay)

Active TB infection —> Bactericidal ( 2 or more drugs)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Second line agents

A

clofazmine

amikacin

ciprofloxcin

levofloxcin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

which drug is a potent CYP450 inducer

A

rifampin — this causes drug drug interactions

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

best drug for HIV/AIDs patients

A

rifabutin since its a less CYP450 inducer

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

adverse effects of isoniazid

A
  • Hepatoxicity - if theres more of the metabolite - fast acetylation

Peripheral neuropathy - if theres more of the pt compound - slow acetylation

anemia and
drug induced SLE (REVERSIBLE)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly

antimicrobial (3 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions