Antimicrobials - Use/activity ---> Drug/Class Flashcards

1
Q

Streptococci, Nieserria, oral anaerobes

A

Penicillins

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2
Q

Methicillin sensitive staphylococci

A

nafcillin

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3
Q

G+ not staph and some G-

A

Amino penicillins (ampicillin)

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4
Q

Broad-spectrum G+ organisms; G - organisms including Pseudomonas not staph

A

Extended spectrum penicillins (piperacillin)

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5
Q

expand the activity of ampiamox/piperacillin and ticarcillin to include anerobes and more G- and methicillin sens. Staph.

A

Clavulanic acid (Beta lactamase inhibitors)

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6
Q

Good for G+ organisms many G- no cns penetration

A

Cefazolin (1st gen Ceph)

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7
Q

Some anaerobic activity better at G-

A

Cefuroxime (2nd gen Ceph)

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8
Q

Active against Pseudomonas ; broader G- activity penetrate CNS ; less G+ activity

A

Ceftriaxone (3rd gen Ceph)

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9
Q

Broadest specturm ceph ; nosocomial G- org. and G+ Cocci including meth. send. staph

A

Cefepime (4th gen Ceph)

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10
Q

Aerobic G- bacilli ( those with serious penicillin allergy)

A

Aztreobactam

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11
Q

VERY broad spectrum ; many G- ; resistant nosocomial, some enterococi, MSSA, anaerobes

A

Imipenem-cilastatin, meropenem, ertapenem, doripenem

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12
Q

Coag +/- Staph and other gram + bacteria

A

Vanco

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13
Q

G+ including MRSA and non-faecalis VRE

A

Quinupristin-dalfopristin

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14
Q

Coag +/- staph other G+ including glycopeptide resistant enterococci

A

Daptomycin

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15
Q

Coag +/- staph other G+ including glycopeptide resistant enterococci and NOCARDIA

A

Linezoled

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16
Q

G- bacilli , almonella , Pneumocystis Jirovecii, Nocardia

A

TMP/SMX

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17
Q

Broad spectrum including legionella ; strept or anaerobes

A

Cipro/levo/moxifloxacin

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18
Q

Anaerobes ; Giardia, Trichomonas , C. Diff

A

Metronidazole

19
Q

TB ; meningococcal and H ingluenzae prophylaxis

A

Rifampin

20
Q

G- bacilli ; no activity in anaerobic conditions

A

aminoglycosides

21
Q

Broad spectru ; Salmonella anaerobes , rickettsia , brucella , bartonella, bu limited due to toxicity

A

Chloramphenicol

22
Q

Anaerobes; G- cocci

A

Clindamycin

23
Q

Broad Spectrum ; spirochetes and rickettsia

A

Tetracyclines

24
Q

broad spectrum , MRSA anaerobes , G-

A

Tigecycline

25
Q

G + cocci , Legionella, Mycoplasma

A

Erythromycin

26
Q

mycobacteria and toxo due to high IC conc.

A

Azithromycin, Clarithromycin

27
Q

enhanced towards G- ; macrolide resistant Strepto. Pneumo. ; MRSA

A

Telithromycin

28
Q

candidiasis ; if + ampho then cryptococcus

A

Flucytosine

29
Q

Mucosal candidiasis, pulmonary histoplasmosis

A

Ketoconazole

30
Q

Histo and Blasto

A

Itraconazole

31
Q

Candidiasis, cryptococcosis , coccidioidomycosis

A

Fluconazole

32
Q

invasive aspergillosis, fusarium and scedosporium , empiric for febrile neutropenia

A

Voriconazole

33
Q

prophylaxis of invasive fungal infections in Icomp pt. ; zygomycoses, reractory candida

A

Posaconazole

34
Q

candida, invasive aspergillosis

A

Caspofungin

35
Q

Eso. Candida, prophy of invasive candida in BM transplant , empiric in febrile neutropenia

A

MIcafungin

36
Q

candidemia, eso candida, systemic candida

A

Anidulafungin

37
Q

HSV ecephalitis ; herpes zoster

A

acyclovir

38
Q

HSV, zoster

A

Famciclovir

39
Q

CMV/HSV

A

Fanciclovir, valgan- , foscarnet and Cidofovir

40
Q

Influenza A tx and prophylaxia

A

Amantadine, rimantadine

41
Q

Influenza A and B

A

Zanamavir and Oseltamavir

42
Q

RSV, Hepatitis C i + IFN alpha

A

Ribavirin

43
Q

IFN alpha

A

Hep B and C

44
Q

Entecavir

A

Hep B