Antimicrobials - Use/activity ---> Drug/Class

Question 1

Streptococci, Nieserria, oral anaerobes

Answer 1

Penicillins

Question 2

Methicillin sensitive staphylococci

Answer 2

nafcillin

Question 3

G+ not staph and some G-

Answer 3

Amino penicillins (ampicillin)

Question 4

Broad-spectrum G+ organisms; G - organisms including Pseudomonas not staph

Answer 4

Extended spectrum penicillins (piperacillin)

Question 5

expand the activity of ampiamox/piperacillin and ticarcillin to include anerobes and more G- and methicillin sens. Staph.

Answer 5

Clavulanic acid (Beta lactamase inhibitors)

Question 6

Good for G+ organisms many G- no cns penetration

Answer 6

Cefazolin (1st gen Ceph)

Question 7

Some anaerobic activity better at G-

Answer 7

Cefuroxime (2nd gen Ceph)

Question 8

Active against Pseudomonas ; broader G- activity penetrate CNS ; less G+ activity

Answer 8

Ceftriaxone (3rd gen Ceph)

Question 9

Broadest specturm ceph ; nosocomial G- org. and G+ Cocci including meth. send. staph

Answer 9

Cefepime (4th gen Ceph)

Question 10

Aerobic G- bacilli ( those with serious penicillin allergy)

Answer 10

Aztreobactam

Question 11

VERY broad spectrum ; many G- ; resistant nosocomial, some enterococi, MSSA, anaerobes

Answer 11

Imipenem-cilastatin, meropenem, ertapenem, doripenem

Question 12

Coag +/- Staph and other gram + bacteria

Answer 12

Vanco

Question 13

G+ including MRSA and non-faecalis VRE

Answer 13

Quinupristin-dalfopristin

Question 14

Coag +/- staph other G+ including glycopeptide resistant enterococci

Answer 14

Daptomycin

Question 15

Coag +/- staph other G+ including glycopeptide resistant enterococci and NOCARDIA

Answer 15

Linezoled

Question 16

G- bacilli , almonella , Pneumocystis Jirovecii, Nocardia

Answer 16

TMP/SMX

Question 17

Broad spectrum including legionella ; strept or anaerobes

Answer 17

Cipro/levo/moxifloxacin

Question 18

Anaerobes ; Giardia, Trichomonas , C. Diff

Answer 18

Metronidazole

Question 19

TB ; meningococcal and H ingluenzae prophylaxis

Answer 19

Rifampin

Question 20

G- bacilli ; no activity in anaerobic conditions

Answer 20

aminoglycosides

Question 21

Broad spectru ; Salmonella anaerobes , rickettsia , brucella , bartonella, bu limited due to toxicity

Answer 21

Chloramphenicol

Question 22

Anaerobes; G- cocci

Answer 22

Clindamycin

Question 23

Broad Spectrum ; spirochetes and rickettsia

Answer 23

Tetracyclines

Question 24

broad spectrum , MRSA anaerobes , G-

Answer 24

Tigecycline

Question 25

G + cocci , Legionella, Mycoplasma

Answer 25

Erythromycin

Question 26

mycobacteria and toxo due to high IC conc.

Answer 26

Azithromycin, Clarithromycin

Question 27

enhanced towards G- ; macrolide resistant Strepto. Pneumo. ; MRSA

Answer 27

Telithromycin

Question 28

candidiasis ; if + ampho then cryptococcus

Answer 28

Flucytosine

Question 29

Mucosal candidiasis, pulmonary histoplasmosis

Answer 29

Ketoconazole

Question 30

Histo and Blasto

Answer 30

Itraconazole

Question 31

Candidiasis, cryptococcosis , coccidioidomycosis

Answer 31

Fluconazole

Question 32

invasive aspergillosis, fusarium and scedosporium , empiric for febrile neutropenia

Answer 32

Voriconazole

Question 33

prophylaxis of invasive fungal infections in Icomp pt. ; zygomycoses, reractory candida

Answer 33

Posaconazole

Question 34

candida, invasive aspergillosis

Answer 34

Caspofungin

Question 35

Eso. Candida, prophy of invasive candida in BM transplant , empiric in febrile neutropenia

Answer 35

MIcafungin

Question 36

candidemia, eso candida, systemic candida

Answer 36

Anidulafungin

Question 37

HSV ecephalitis ; herpes zoster

Answer 37

acyclovir

Question 38

HSV, zoster

Answer 38

Famciclovir

Question 39

CMV/HSV

Answer 39

Fanciclovir, valgan- , foscarnet and Cidofovir

Question 40

Influenza A tx and prophylaxia

Answer 40

Amantadine, rimantadine

Question 41

Influenza A and B

Answer 41

Zanamavir and Oseltamavir

Question 42

RSV, Hepatitis C i + IFN alpha

Answer 42

Ribavirin

Question 43

IFN alpha

Answer 43

Hep B and C

Question 44

Entecavir

Answer 44

Hep B