Antimicrobials - Aminoglycosides, sufos, quinolones Flashcards
Bactericidal, Binds to 30s,
Tx for ENDOCARDITIS
SE: Nephrotoxic, Ototoxic
Gentamycin
Ocular infection tx
Requires O2 for transport
Tobramycin
TB
Streptomycin
Drug resistant Gonorrhea
Spectinomycin
Wides spectrum activity, Pseudomonas activity, narrow therapeutic window
Ototoxic
Amikacin
Tx for hepatic encephalopathy
Teratogen
Neomycin
Blocks Dihidropropteroate synthase
Sulofnamide
Blocks DHF reductase
Trimetrhoprim
Sequential blockade in folate synthesis, urinary tract infections
Co-Tri
SE: hypersensitivity(SJS, TEN), kernikterus, hemolysis in patients with COPD
Cotrimoxazole
Treatment for burn patients
Silver sulfadiazine
2nd generation quinolone, Tx for UTI and GIT infections
SE: Tendinitis, tendon rupture
Ciprofloxacin
3rd gen quinolone, Tx for pulmonary infections
Levofloxacin
4th gen quinolone
Broad spectrum of activity, anaerobic coverage, Tx of ocular infections
Moxifloxacin
4th gen quinolone
SE: DM
gatifloxacin