Antimicrobials Flashcards
MAC Prophylaxis, drug and CD4 count
Azithromycin, CD4 less than 50
Toxoplasmosis prophylaxis, drug and CD4 count
Bactrim or dapsone, CD4 less than 100
PJP prophylaxis, drug and CD4 count
Bactrim or dapsone, CD4 less than 200
Orbital cellulitis organism and tx
Staph or strep, IV vanco + cephalosporin
Salivary gland infection or stone organism and tx
S aureus, cephalosporin and duct dilation
Peritonsillar abscess organisms and tx
MRSA or GAS, Clindamycin or Ampicillin/sulbactam
Otitis externa organisms and tx
S pneumo, H flu, M catarhallis, topical flouroquinolone
Otitis media
S pneumo, H flu, M catarhallis, augmentin or amoxicillin
Pneumocystis jerovecii
Bactrim or pentamidine
Prostatitis
> 35 E coli, flouroquinolone or bactrim
Orchitis/Epididymitis
> 35 E coli, Cipro
UTI
E coli; flouroquinolone or bactrim
Pyelonephritis
E coli; Ciprofloxacin or levofloxacin
Endocarditis
Staph (acute) or strep (subacute), Amoxicillin or clindamycin if allergic
Acute rheumatic fever
Strep, amoxicillin or macrolide if allergic
Epiglottits pathogen
H flu
Pertussus
Bordatella pertussis, clarithromycin, azithromycin, bactrim
Healthy outpatient CAP
Strep pneumo, flouroquinolone, macrolide or doxy
Comorbid CAP
Strep pneumo; flouroquin, macrolide or doxy PLUS beta lactam (amoxicillin etc)
Inpatient CAP
Strep pneumo; macrolide + beta lactam
HAP
pseudomonas (>48 hrs after admission); piperacillin/tazobactam + levo, cipro, or tobramycin
Legionella
Azith, cipro, or levo
Walking pneumonia
Mycoplasma, macrolides
Aspiration pneumonia
Klebsiella, cephalosporins
Valley fever (sw desert)
Coccidioides, itraconazole or fluconazole
Soil fungal pneumo, can cause meningitis
criptococcus, Amphotericin B
Fungal pneumo, birds, bats, or Mississippi valley
Histoplasmosis, Amphotericin B
H. pylori
PPI + Amoxicillin + Metronidazole or clarithromycin
Cholagitis
E coli; piperacillin/tazobactam or ticaracillin/clavulanate or ciprofloxacin
Wilsons disease treatment
Penicillamine
Appendicitis abx
piperacillin/tazobactam
Diverticulitis abx
Metronidazole + quinolone
Bloody diarrhea, abd tenderness, No fever
E. Coli. NO ABX because it could cause HUS
Travelers diarrhea classification
3 loose stools in less than 24 hrs
Travelers diarrhea tx
Flouroquinolones, antimotility agents
C diff
Metronidazole is 1st line
Oral Vanco 2nd line
NO antimotility
Trichomonas
Trichomonas vaginalis
Metronidazole or tinidazole
treat partner
Gonorrhea
Ceftriaxone
treat partner
Chlamydia
Azithromycin in one dose or
Doxycycline x 7 days
Treat partner
PID
Ceftriaxone plus doxycycline
Chancroid
H ducreyi
Azith or eryth
ceftriaxone
cipro
Syphilis
Treponema palladium less than 1 yr: one dose of pen G greater than1 yr: Pen G multi dose Allergy to Pen: Doxy or azith Preg + Pen allergic: desensitize and give Pen G
Three classes of abx used in Klebsiella pneumonia
Aminoglycosides
Cephalosporin
Flouroquinolone
Two abx classes used to treat legionella
Macrolides
flouroquinolones
Pseudomonas treatment classes
Beta lactam + quinolone or aminoglycoside
Quinolone + aminoglycoside
MRSA pneumonia treatment
Vanc or linezolid + levo or cipro
ICU strep pneumo treatment
Beta lactam + macrolide or flouroquin
Inpatient non ICU strep pneumo treatment
Beta lactam + macrolide
CAP with comorbidities
Flouro, doxy, or macrolide + beta lactam
Healthy CAP treatment
Flouro, doxy or macrolide
Aminoglycosides
Amikacin Gentomycin streptomycin tobramycin neomycin
Macrolides
Erythromycin
Azithromycin
Clarithrmycin
PJP treatment
Bactrim or pentamidine
3 abx regimins to treat diverticulitis
Metro and cipro
augmentin
bactrim