Antimicrobials Flashcards
Benzylpenicillin-Na/K
Time-dependent bactericidal
Inhibits cell wall synthesis
Benzylpenicillin-procaine
Time-dependent bactericidal
Inhibits cell wall synthesis
Benzylpenicillin-benzathine
- Time-dependent bactericidal
- Narrow spectrum penicillin
(Inhibits cell wall synthesis)
Phenyoxymethyl-penicillin
- Time-dependent bactericidal
- narrow spectrum penicillin
(Inhibits cell wall synthesis)
Oxacillin
Time-dependent bactericidal
Penicillinase stable penicillin
(Inhibits cell wall synthesis)
Cloxacillin
Time-dependent bactericidal
Penicillinase stable penicillin
(Inhibits cell wall synthesis)
Dicloxacillin
Time-dependent bactericidal
Penicillinase stable penicillin
(Inhibits cell wall synthesis)
Flucloxacillim
Time-dependent bactericidal
Penicillinase stable penicillin
(Inhibits cell wall synthesis)
Amoxicillin
Time-dependent bactericidal
Broad spectrum penicillin
(Inhibits cell wall synthesis)
Ampicillin
Time-dependent bactericidal
Broad spectrum penicillin
(Inhibits cell wall synthesis)
Ticarcillin
Time-dependent bactericidal
penicillin against pseudomonas
(Inhibits cell wall synthesis)
Piperacillin
Time-dependent bactericidal
penicillin acting against pseudomonas
(Inhibits cell wall synthesis)
Clavulanic acid
MOA: Time-dependent bactericidal
Group: Betalactamase inhibitor
Action: Inhibits cell wall synthesis
Sulbactam
MOA: Time-dependent bactericidal
Group: Betalactamase inhibitor
Action: Inhibits cell wall synthesis
Tazobactam
MOA: Time-dependent bactericidal
Group: Betalactamase inhibitor
Action: Inhibits cell wall synthesis
Cephazoline
MOA: Time-dependent bactericidal
Group: 1st generation cephalosporin
Action: Inhibits cell wall synthesis
Cephapirin
MOA: Time-dependent bactericidal
Group: 1st generation cephalosporin
Action: Inhibits cell wall synthesis
Cefadroxil
MOA: Time-dependent bactericidal
Group: 1st generation cephalosporin
Action: Inhibits cell wall synthesis
Cephalexin
MOA: Time-dependent bactericidal
Group: 1st generation cephalosporin
Action: Inhibits cell wall synthesis
Cefuroxime
MOA: Time-dependent bactericidal
Group: 2nd generation cephalosporin
Action: Inhibits cell wall synthesis
Ceftiofur
MOA: Time-dependent bactericidal
Group: 3rd generation cephalosporin
Action: Inhibits cell wall synthesis
Cefovecin
MOA: Time-dependent bactericidal
Group: 3rd generation cephalosporin
Action: Inhibits cell wall synthesis
Ceftriaxone
MOA: Time-dependent bactericidal
Group: 3rd generation cephalosporin
Action: Inhibits cell wall synthesis
Cefotaxime
MOA: Time-dependent bactericidal
Group: 3rd generation cephalosporin
Action: Inhibits cell wall synthesis
Ceftazidime
MOA: Time-dependent bactericidal
Group: 3rd generation cephalosporin
Action: Inhibits cell wall synthesis
Cefoperazone
MOA: Time-dependent bactericidal
Group: 3rd generation cephalosporin
Action: Inhibits cell wall synthesis
Cefquinome
MOA: Time-dependent bactericidal
Group: 4th generation cephalosporin
Action: Inhibits cell wall synthesis
Imipenem
MOA: Time-dependent bactericidal
Group: Carbapenems
Action: Inhibits cell wall synthesis
Meropenem
MOA: Time-dependent bactericidal
Group: Carbapenems
Action: Inhibits cell wall synthesis
Aztreonam
MOA: Time-dependent bactericidal
Group: Monobactams
Action: Inhibits cell wall synthesis
Tigemonam
MOA: Time-dependent bactericidal
Group: Monobactams
Action: Inhibits cell wall synthesis
Streptomycin
MOA: Concentration-dependent bactericidal
Group: Aminoglycosides
Action: Inhibition of protein synthesis (30s), mistranslation
Neomycin
MOA: Concentration-dependent bactericidal
Group: Aminoglycosides
Action: Inhibition of protein synthesis (30s), mistranslation
Paromomycin
MOA: Concentration-dependent bactericidal
Group: Aminoglycosides
Action: Inhibition of protein synthesis (30s), mistranslation
Kanamycin
MOA: Concentration-dependent bactericidal
Group: Aminoglycosides
Action: Inhibition of protein synthesis (30s), mistranslation
Gentamicin
MOA: Concentration-dependent bactericidal
Group: Aminoglycosides
Action: Inhibition of protein synthesis (30s), mistranslation
Tobramycin
MOA: Concentration-dependent bactericidal
Group: Aminoglycosides
Action: Inhibition of protein synthesis (30s), mistranslation
Amikacin
MOA: Concentration-dependent bactericidal
Group: Aminoglycosides
Action: Inhibition of protein synthesis (30s), mistranslation
Apramycin
MOA: Concentration-dependent bactericidal
Group: Aminoglycosides
Action: Inhibition of protein synthesis (30s), mistranslation
Spectinomycin
MOA: Bacteriostatic
Group: Aminoglycosides
Action: Inhibition of protein synthesis (30s), mistranslation
Chlortetracycline
MOA: Bacteriostatic
Group: short-acting TTCs
Action: Inhibition of protein synthesis (30s)
Oxytetracycline
MOA: Bacteriostatic
Group: short-acting TTCs
Action: Inhibition of protein synthesis (30s)
Tetracycline
MOA: Bacteriostatic
Group: short-acting TTCs
Action: Inhibition of protein synthesis (30s)
Doxycycline
MOA: Bacteriostatic
Group: long-acting TTCs
Action: Inhibition of protein synthesis (30s)
Minocycline
MOA: Bacteriostatic
Group: long-acting TTCs
Action: Inhibition of protein synthesis (30s)
Erythromycin
MOA: Bacteriostatic
Group: Macrolides
Action: Inhibition of protein synthesis (50S)
Azithromycin
MOA: Bacteriostatic
Group: Macrolides
Action: Inhibition of protein synthesis (50S)
Clarithromycin
MOA: Bacteriostatic
Group: Macrolides
Action: Inhibition of protein synthesis (50S)
Spiramycin
MOA: Bacteriostatic
Group: Macrolides
Action: Inhibition of protein synthesis (50S)
Tylosin
MOA: Bacteriostatic
Group: Macrolides
Action: Inhibition of protein synthesis (50S)
Tylvalosin
MOA: Bacteriostatic
Group: Macrolides
Action: Inhibition of protein synthesis (50S)
Tilmicosin
MOA: Bacteriostatic
Group: Macrolides
Action: Inhibition of protein synthesis (50S)
Tulathromycin
MOA: Bacteriostatic
Group: Macrolides
Action: Inhibition of protein synthesis (50S)
Gamithromycin
MOA: Bacteriostatic
Group: Macrolides
Action: Inhibition of protein synthesis (50S)
Tildipirosin
MOA: Bacteriostatic
Group: Macrolides
Action: Inhibition of protein synthesis (50S)
Lincomycin
MOA: Bacteriostatic
Group: Lincosamides
Action: Inhibition of protein synthesis (50S)
Clindamycin
MOA: Bacteriostatic
Group: Lincosamides
Action: Inhibition of protein synthesis (50S)
Tiamulin
MOA: Bacteriostatic
Group: Pleuromutilins
Action: Inhibition of protein synthesis (50S)
Valnemulin
MOA: Bacteriostatic
Group: Pleuromutilins
Action: Inhibition of protein synthesis (50S)
Chloramphenicol
MOA: Bacteriostatic
Group: Phenicols
Action: Inhibition of protein synthesis (50S)
Florfenicol
MOA: Bacteriostatic
Group: Phenicols
Action: Inhibition of protein synthesis (50S)
Thiamphenicol
MOA: Bacteriostatic
Group: Phenicols
Action: Inhibition of protein synthesis (50S)
Bacitracin
MOA: Concentration-dependent bactericidal
Group: Polypeptide ABs
Action: Act like a cationic detergent
Polymyxin B
MOA: Concentration-dependent bactericidal
Group: Polypeptide ABs
Action: Act like a cationic detergent
Polymyxin E (Colisitin)
MOA: Concentration-dependent bactericidal
Group: Polypeptide ABs
Action: Act like a cationic detergent
Vancomycin
MOA: Time-dependent bactericidal
Group: Glycopeptide ABs
Action: Inhibition of cell wall synthesis
Teicoplanin
MOA: Time-dependent bactericidal
Group: Glycopeptide ABs
Action: Inhibition of cell wall synthesis
Rifampicin
MOA: Time-dependent bactericidal
Group: Rifamycines
Action: Inhibition of bacterial DNA-dependent RNA polymerase
Mupirocin
MOA: bactericidal
Group: Pseudomonic acid
Action: Inhibition of cell wall synthesis
Fosfomycin
MOA: bactericidal
Group: Phosphonic acid derivatives
Action: Inhibition of cell wall synthesis
Fusidic acid
MOA: Bacteriostatic
Action: Inhibition of protein synthesis
Sulfadimidine
MOA: Separately bacteriostatic, in combination time-dependent bactericidal
Group: Sulphonamides
Action: Inhibition of folic acid synthesis
Sulfadiazine
MOA: Separately bacteriostatic, in combination time-dependent bactericidal
Group: Sulphonamides
Action: Inhibition of folic acid synthesis
Sulfachlorpyridazine
MOA: Separately bacteriostatic, in combination time-dependent bactericidal
Group: Sulphonamides
Action: Inhibition of folic acid synthesis
Sulfachlorpyrazine
MOA: Separately bacteriostatic, in combination time-dependent bactericidal
Group: Sulphonamides
Action: Inhibition of folic acid synthesis
Sulfamethoxasole
MOA: Separately bacteriostatic, in combination time-dependent bactericidal
Group: Sulphonamides
Action: Inhibition of folic acid synthesis
Sulfadoxine
MOA: Separately bacteriostatic, in combination time-dependent bactericidal
Group: Sulphonamides
Action: Inhibition of folic acid synthesis
Sulfaquinoxaline
MOA: Separately bacteriostatic, in combination time-dependent bactericidal
Group: Sulphonamides
Action: Inhibition of folic acid synthesis
Sulfasalazine
MOA: Separately bacteriostatic, in combination time-dependent bactericidal
Group: Sulphonamides
Action: Inhibition of folic acid synthesis
Trimethoprim
MOA: Separately bacteriostatic, in combination time-dependent bactericidal
Group: Diaminopyrimidines
Action: Inhibition of folic acid synthesis
Baquiloprim
MOA: Separately bacteriostatic, in combination time-dependent bactericidal
Group: Diaminopyrimidines
Action: Inhibition of folic acid synthesis
Nalidixic acid
MOA: Concentration-dependent bactericidal
Group: 1st generation fluoroquinolone
Action: Inhibition of DNA synthesis
Flumequine
MOA: Concentration-dependent bactericidal
Group: 2nd generation fluoroquinolone
Action: Inhibition of DNA synthesis
Norfloxacin
MOA: Concentration-dependent bactericidal
Group: 2nd generation fluoroquinolone
Action: Inhibition of DNA synthesis
Orbifloxacin
MOA: Concentration-dependent bactericidal
Group: 2nd generation fluoroquinolone
Action: Inhibition of DNA synthesis
Ciprofloxacin
MOA: Concentration-dependent bactericidal
Group: 2nd generation fluoroquinolone
Action: Inhibition of DNA synthesis
Enrofloxacin
MOA: Concentration-dependent bactericidal
Group: 2nd generation fluoroquinolone
Action: Inhibition of DNA synthesis
Danofloxacin
MOA: Concentration-dependent bactericidal
Group: 2nd generation fluoroquinolone
Action: Inhibition of DNA synthesis
Difloxacin
MOA: Concentration-dependent bactericidal
Group: 2nd generation fluoroquinolone
Action: Inhibition of DNA synthesis
Marbofloxacin
MOA: Concentration-dependent bactericidal
Group: 2nd generation fluoroquinolone
Action: Inhibition of DNA synthesis
Levofloxacin
MOA: Concentration-dependent bactericidal
Group: 3rd generation fluoroquinolone
Action: Inhibition of DNA synthesis
Sparfloxacin
MOA: Concentration-dependent bactericidal
Group: 3rd generation fluoroquinolone
Action: Inhibition of DNA synthesis
Pradofloxacin
MOA: Concentration-dependent bactericidal
Group: 4th generation fluoroquinolone
Action: Inhibition of DNA synthesis
Moxifloxacin
MOA: Concentration-dependent bactericidal
Group: 4th generation fluoroquinolone
Action: Inhibition of DNA synthesis
Nitrofurantoin
MOA: bactericidal
Group: Nitrofurans
Action: Destroys the DNA of bacteria
Furazolidine
MOA: bactericidal
Group: nitrofurans
Action: Destroys the DNA of bacteria
Metronidazole
MOA: Concentration-dependent bactericidal
Group: Nitroimidazoles
Action: Destroys the DNA of bacteria
Ronidazole
MOA: Concentration-dependent bactericidal
Group: Nitroimidazoles
Action: Destroys the DNA of bacteria
Tinidazole
MOA: Concentration-dependent bactericidal
Group: Nitroimidazoles
Action: Destroys the DNA of bacteria