Antimicrobials Flashcards

1
Q

Benzylpenicillin-Na/K

A

Time-dependent bactericidal

Inhibits cell wall synthesis

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2
Q

Benzylpenicillin-procaine

A

Time-dependent bactericidal

Inhibits cell wall synthesis

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3
Q

Benzylpenicillin-benzathine

A
  • Time-dependent bactericidal
  • Narrow spectrum penicillin
    (Inhibits cell wall synthesis)
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4
Q

Phenyoxymethyl-penicillin

A
  • Time-dependent bactericidal
  • narrow spectrum penicillin
    (Inhibits cell wall synthesis)
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5
Q

Oxacillin

A

Time-dependent bactericidal
Penicillinase stable penicillin
(Inhibits cell wall synthesis)

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6
Q

Cloxacillin

A

Time-dependent bactericidal
Penicillinase stable penicillin
(Inhibits cell wall synthesis)

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7
Q

Dicloxacillin

A

Time-dependent bactericidal
Penicillinase stable penicillin
(Inhibits cell wall synthesis)

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8
Q

Flucloxacillim

A

Time-dependent bactericidal
Penicillinase stable penicillin
(Inhibits cell wall synthesis)

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9
Q

Amoxicillin

A

Time-dependent bactericidal
Broad spectrum penicillin
(Inhibits cell wall synthesis)

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10
Q

Ampicillin

A

Time-dependent bactericidal
Broad spectrum penicillin
(Inhibits cell wall synthesis)

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11
Q

Ticarcillin

A

Time-dependent bactericidal
penicillin against pseudomonas
(Inhibits cell wall synthesis)

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12
Q

Piperacillin

A

Time-dependent bactericidal
penicillin acting against pseudomonas
(Inhibits cell wall synthesis)

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13
Q

Clavulanic acid

A

MOA: Time-dependent bactericidal

Group: Betalactamase inhibitor
Action: Inhibits cell wall synthesis

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14
Q

Sulbactam

A

MOA: Time-dependent bactericidal

Group: Betalactamase inhibitor
Action: Inhibits cell wall synthesis

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15
Q

Tazobactam

A

MOA: Time-dependent bactericidal

Group: Betalactamase inhibitor
Action: Inhibits cell wall synthesis

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16
Q

Cephazoline

A

MOA: Time-dependent bactericidal

Group: 1st generation cephalosporin
Action: Inhibits cell wall synthesis

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17
Q

Cephapirin

A

MOA: Time-dependent bactericidal

Group: 1st generation cephalosporin
Action: Inhibits cell wall synthesis

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18
Q

Cefadroxil

A

MOA: Time-dependent bactericidal

Group: 1st generation cephalosporin
Action: Inhibits cell wall synthesis

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19
Q

Cephalexin

A

MOA: Time-dependent bactericidal

Group: 1st generation cephalosporin
Action: Inhibits cell wall synthesis

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20
Q

Cefuroxime

A

MOA: Time-dependent bactericidal

Group: 2nd generation cephalosporin
Action: Inhibits cell wall synthesis

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21
Q

Ceftiofur

A

MOA: Time-dependent bactericidal

Group: 3rd generation cephalosporin
Action: Inhibits cell wall synthesis

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22
Q

Cefovecin

A

MOA: Time-dependent bactericidal

Group: 3rd generation cephalosporin
Action: Inhibits cell wall synthesis

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23
Q

Ceftriaxone

A

MOA: Time-dependent bactericidal

Group: 3rd generation cephalosporin
Action: Inhibits cell wall synthesis

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24
Q

Cefotaxime

A

MOA: Time-dependent bactericidal

Group: 3rd generation cephalosporin
Action: Inhibits cell wall synthesis

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25
Q

Ceftazidime

A

MOA: Time-dependent bactericidal

Group: 3rd generation cephalosporin
Action: Inhibits cell wall synthesis

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26
Q

Cefoperazone

A

MOA: Time-dependent bactericidal

Group: 3rd generation cephalosporin
Action: Inhibits cell wall synthesis

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27
Q

Cefquinome

A

MOA: Time-dependent bactericidal

Group: 4th generation cephalosporin
Action: Inhibits cell wall synthesis

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28
Q

Imipenem

A

MOA: Time-dependent bactericidal

Group: Carbapenems
Action: Inhibits cell wall synthesis

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29
Q

Meropenem

A

MOA: Time-dependent bactericidal

Group: Carbapenems
Action: Inhibits cell wall synthesis

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30
Q

Aztreonam

A

MOA: Time-dependent bactericidal

Group: Monobactams
Action: Inhibits cell wall synthesis

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31
Q

Tigemonam

A

MOA: Time-dependent bactericidal

Group: Monobactams
Action: Inhibits cell wall synthesis

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32
Q

Streptomycin

A

MOA: Concentration-dependent bactericidal

Group: Aminoglycosides
Action: Inhibition of protein synthesis (30s), mistranslation

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33
Q

Neomycin

A

MOA: Concentration-dependent bactericidal

Group: Aminoglycosides
Action: Inhibition of protein synthesis (30s), mistranslation

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34
Q

Paromomycin

A

MOA: Concentration-dependent bactericidal

Group: Aminoglycosides
Action: Inhibition of protein synthesis (30s), mistranslation

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35
Q

Kanamycin

A

MOA: Concentration-dependent bactericidal

Group: Aminoglycosides
Action: Inhibition of protein synthesis (30s), mistranslation

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36
Q

Gentamicin

A

MOA: Concentration-dependent bactericidal

Group: Aminoglycosides
Action: Inhibition of protein synthesis (30s), mistranslation

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37
Q

Tobramycin

A

MOA: Concentration-dependent bactericidal

Group: Aminoglycosides
Action: Inhibition of protein synthesis (30s), mistranslation

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38
Q

Amikacin

A

MOA: Concentration-dependent bactericidal

Group: Aminoglycosides
Action: Inhibition of protein synthesis (30s), mistranslation

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39
Q

Apramycin

A

MOA: Concentration-dependent bactericidal

Group: Aminoglycosides
Action: Inhibition of protein synthesis (30s), mistranslation

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40
Q

Spectinomycin

A

MOA: Bacteriostatic

Group: Aminoglycosides
Action: Inhibition of protein synthesis (30s), mistranslation

41
Q

Chlortetracycline

A

MOA: Bacteriostatic

Group: short-acting TTCs
Action: Inhibition of protein synthesis (30s)

42
Q

Oxytetracycline

A

MOA: Bacteriostatic

Group: short-acting TTCs
Action: Inhibition of protein synthesis (30s)

43
Q

Tetracycline

A

MOA: Bacteriostatic

Group: short-acting TTCs
Action: Inhibition of protein synthesis (30s)

44
Q

Doxycycline

A

MOA: Bacteriostatic

Group: long-acting TTCs
Action: Inhibition of protein synthesis (30s)

45
Q

Minocycline

A

MOA: Bacteriostatic

Group: long-acting TTCs
Action: Inhibition of protein synthesis (30s)

46
Q

Erythromycin

A

MOA: Bacteriostatic

Group: Macrolides
Action: Inhibition of protein synthesis (50S)

47
Q

Azithromycin

A

MOA: Bacteriostatic

Group: Macrolides
Action: Inhibition of protein synthesis (50S)

48
Q

Clarithromycin

A

MOA: Bacteriostatic

Group: Macrolides
Action: Inhibition of protein synthesis (50S)

49
Q

Spiramycin

A

MOA: Bacteriostatic

Group: Macrolides
Action: Inhibition of protein synthesis (50S)

50
Q

Tylosin

A

MOA: Bacteriostatic

Group: Macrolides
Action: Inhibition of protein synthesis (50S)

51
Q

Tylvalosin

A

MOA: Bacteriostatic

Group: Macrolides
Action: Inhibition of protein synthesis (50S)

52
Q

Tilmicosin

A

MOA: Bacteriostatic

Group: Macrolides
Action: Inhibition of protein synthesis (50S)

53
Q

Tulathromycin

A

MOA: Bacteriostatic

Group: Macrolides
Action: Inhibition of protein synthesis (50S)

54
Q

Gamithromycin

A

MOA: Bacteriostatic

Group: Macrolides
Action: Inhibition of protein synthesis (50S)

55
Q

Tildipirosin

A

MOA: Bacteriostatic

Group: Macrolides
Action: Inhibition of protein synthesis (50S)

56
Q

Lincomycin

A

MOA: Bacteriostatic

Group: Lincosamides
Action: Inhibition of protein synthesis (50S)

57
Q

Clindamycin

A

MOA: Bacteriostatic

Group: Lincosamides
Action: Inhibition of protein synthesis (50S)

58
Q

Tiamulin

A

MOA: Bacteriostatic

Group: Pleuromutilins
Action: Inhibition of protein synthesis (50S)

59
Q

Valnemulin

A

MOA: Bacteriostatic

Group: Pleuromutilins
Action: Inhibition of protein synthesis (50S)

60
Q

Chloramphenicol

A

MOA: Bacteriostatic

Group: Phenicols
Action: Inhibition of protein synthesis (50S)

61
Q

Florfenicol

A

MOA: Bacteriostatic

Group: Phenicols
Action: Inhibition of protein synthesis (50S)

62
Q

Thiamphenicol

A

MOA: Bacteriostatic

Group: Phenicols
Action: Inhibition of protein synthesis (50S)

63
Q

Bacitracin

A

MOA: Concentration-dependent bactericidal

Group: Polypeptide ABs
Action: Act like a cationic detergent

64
Q

Polymyxin B

A

MOA: Concentration-dependent bactericidal

Group: Polypeptide ABs
Action: Act like a cationic detergent

65
Q

Polymyxin E (Colisitin)

A

MOA: Concentration-dependent bactericidal

Group: Polypeptide ABs
Action: Act like a cationic detergent

66
Q

Vancomycin

A

MOA: Time-dependent bactericidal

Group: Glycopeptide ABs
Action: Inhibition of cell wall synthesis

67
Q

Teicoplanin

A

MOA: Time-dependent bactericidal

Group: Glycopeptide ABs
Action: Inhibition of cell wall synthesis

68
Q

Rifampicin

A

MOA: Time-dependent bactericidal

Group: Rifamycines
Action: Inhibition of bacterial DNA-dependent RNA polymerase

69
Q

Mupirocin

A

MOA: bactericidal

Group: Pseudomonic acid
Action: Inhibition of cell wall synthesis

70
Q

Fosfomycin

A

MOA: bactericidal

Group: Phosphonic acid derivatives
Action: Inhibition of cell wall synthesis

71
Q

Fusidic acid

A

MOA: Bacteriostatic

Action: Inhibition of protein synthesis

72
Q

Sulfadimidine

A

MOA: Separately bacteriostatic, in combination time-dependent bactericidal

Group: Sulphonamides
Action: Inhibition of folic acid synthesis

73
Q

Sulfadiazine

A

MOA: Separately bacteriostatic, in combination time-dependent bactericidal

Group: Sulphonamides
Action: Inhibition of folic acid synthesis

74
Q

Sulfachlorpyridazine

A

MOA: Separately bacteriostatic, in combination time-dependent bactericidal

Group: Sulphonamides
Action: Inhibition of folic acid synthesis

75
Q

Sulfachlorpyrazine

A

MOA: Separately bacteriostatic, in combination time-dependent bactericidal

Group: Sulphonamides
Action: Inhibition of folic acid synthesis

76
Q

Sulfamethoxasole

A

MOA: Separately bacteriostatic, in combination time-dependent bactericidal

Group: Sulphonamides
Action: Inhibition of folic acid synthesis

77
Q

Sulfadoxine

A

MOA: Separately bacteriostatic, in combination time-dependent bactericidal

Group: Sulphonamides
Action: Inhibition of folic acid synthesis

78
Q

Sulfaquinoxaline

A

MOA: Separately bacteriostatic, in combination time-dependent bactericidal

Group: Sulphonamides
Action: Inhibition of folic acid synthesis

79
Q

Sulfasalazine

A

MOA: Separately bacteriostatic, in combination time-dependent bactericidal

Group: Sulphonamides
Action: Inhibition of folic acid synthesis

80
Q

Trimethoprim

A

MOA: Separately bacteriostatic, in combination time-dependent bactericidal

Group: Diaminopyrimidines
Action: Inhibition of folic acid synthesis

81
Q

Baquiloprim

A

MOA: Separately bacteriostatic, in combination time-dependent bactericidal

Group: Diaminopyrimidines
Action: Inhibition of folic acid synthesis

82
Q

Nalidixic acid

A

MOA: Concentration-dependent bactericidal

Group: 1st generation fluoroquinolone
Action: Inhibition of DNA synthesis

83
Q

Flumequine

A

MOA: Concentration-dependent bactericidal

Group: 2nd generation fluoroquinolone
Action: Inhibition of DNA synthesis

84
Q

Norfloxacin

A

MOA: Concentration-dependent bactericidal

Group: 2nd generation fluoroquinolone
Action: Inhibition of DNA synthesis

85
Q

Orbifloxacin

A

MOA: Concentration-dependent bactericidal

Group: 2nd generation fluoroquinolone
Action: Inhibition of DNA synthesis

86
Q

Ciprofloxacin

A

MOA: Concentration-dependent bactericidal

Group: 2nd generation fluoroquinolone
Action: Inhibition of DNA synthesis

87
Q

Enrofloxacin

A

MOA: Concentration-dependent bactericidal

Group: 2nd generation fluoroquinolone
Action: Inhibition of DNA synthesis

88
Q

Danofloxacin

A

MOA: Concentration-dependent bactericidal

Group: 2nd generation fluoroquinolone
Action: Inhibition of DNA synthesis

89
Q

Difloxacin

A

MOA: Concentration-dependent bactericidal

Group: 2nd generation fluoroquinolone
Action: Inhibition of DNA synthesis

90
Q

Marbofloxacin

A

MOA: Concentration-dependent bactericidal

Group: 2nd generation fluoroquinolone
Action: Inhibition of DNA synthesis

91
Q

Levofloxacin

A

MOA: Concentration-dependent bactericidal

Group: 3rd generation fluoroquinolone
Action: Inhibition of DNA synthesis

92
Q

Sparfloxacin

A

MOA: Concentration-dependent bactericidal

Group: 3rd generation fluoroquinolone
Action: Inhibition of DNA synthesis

93
Q

Pradofloxacin

A

MOA: Concentration-dependent bactericidal

Group: 4th generation fluoroquinolone
Action: Inhibition of DNA synthesis

94
Q

Moxifloxacin

A

MOA: Concentration-dependent bactericidal

Group: 4th generation fluoroquinolone
Action: Inhibition of DNA synthesis

95
Q

Nitrofurantoin

A

MOA: bactericidal

Group: Nitrofurans
Action: Destroys the DNA of bacteria

96
Q

Furazolidine

A

MOA: bactericidal

Group: nitrofurans
Action: Destroys the DNA of bacteria

97
Q

Metronidazole

A

MOA: Concentration-dependent bactericidal

Group: Nitroimidazoles
Action: Destroys the DNA of bacteria

98
Q

Ronidazole

A

MOA: Concentration-dependent bactericidal

Group: Nitroimidazoles
Action: Destroys the DNA of bacteria

99
Q

Tinidazole

A

MOA: Concentration-dependent bactericidal

Group: Nitroimidazoles
Action: Destroys the DNA of bacteria