antimicrobial therapy (quiz 1, exam 1) Flashcards
8 things to consider before giving drugs
- pathogen
- site of infection
- characteristics of antimicrobials
- route of administration
- duration of therapy
- combinations
- monitoring of antimicrobial therapy
- antimicrobial resistance testing
pathogen: if the pathogen is known, a drug that is __ is chosen
highly selective for that bug
pathogen: if the bug causing the illness is not know, then __ choice is made
an empirical treatment: choose a drug active against the most likely bug in the specific clinical setting
pathogen: also consider __ in the specific community or hospital
patterns of drug resistance
pathogen: broad spectrum drug treatment is used in cases of
- more severe illness and uncertainty about the bug
- in immunocompromised febrile pts
pathogen: once the bug and its drug sensitivities are known, __
empirical is scaled down to definitive regimen
aerobic gram positive bacteria
- Streptococcus
- Enterococcus
- Staphylococcus
- Cornybacterium
- Listeria
aerobic gram negative bacteria
- E. coli (enterobacteriaceae)
- Klebsiella (enterobacteriaceae)
- Enterobacter (enterobacteriaceae)
- Citrobacter (enterobacteriaceae)
- Proteus (enterobacteriaceae)
- Serratia (enterobacteriaceae)
- Salmonella (enterobacteriaceae)
- Shigella (enterobacteriaceae)
- Morganella (enterobacteriaceae)
- Providencia (enterobacteriaceae)
- Pseudomonas
- Heliobacter
- Haemophilus
- Legionella
- Moraxella
- Neisseria
anaerobic gram positive bacteria
- Peptococcus
- Peptostreptococcus
- Clostrida
- Propionibacterium acnes
anaerobic gram negative bacteria
- Bacteroides
2. Fusobacterium
atypicals
- Chlamydia
- Chlamydophila
- Rickettsiae
- Mycoplasma
- Spirochetes (Syphilus, Lyme disease)
- Mycobacterium
Streptococcus
aerobic gram positive bacteria
Enterococcus
aerobic gram positive bacteria
Staphylococcus
aerobic gram positive bacteria
Cornybacterium
aerobic gram positive bacteria
Listeria
aerobic gram positive bacteria
E. coli
(enterobacteriaceae) aerobic gram negative bacteria