antimicrobial side effects Flashcards

1
Q

Hypersensitivity

A

penicillins
cephalosporins
imipenem-cross sensitivity with penicillins

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2
Q

nephrotoxicity

A

aminoglycosides-acute tubular necrosis

vancomycin-enhances toxicity of other drugs

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3
Q

skin rash-low hypersensitivity

A

vancomycin, aztreonam

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4
Q

ototoxicity

A

aminoglycosides: gentamycin

- erythromycin at high doses

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5
Q

hepatitis

A

isoniazid and rifampin, esp >50 yrs and EtOH

tetracyclines: pregnant women

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6
Q

phototoxicity

A

tetracyclines

fluoroquinolones: cirpofloxacin

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7
Q

kernicterus

A

sulfonamides

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8
Q

red man syndrome

A

vancomycin -infusion related toxicity

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9
Q

skin rash/stevens johnson

A

sulfonamides

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10
Q

gray baby syndrome

A

chloramphenicol

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11
Q

arthropathy

A

ciprofloxacin

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12
Q

peripheral neuropathy

A

isoniazid- slow acetylators

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13
Q

discoloration of body fluids

A

rifampin

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14
Q

optic neuritis

A

ethambutol

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15
Q

acute gout

A

ethambutol, pyrazinamide

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