antimicrobial side effects Flashcards
Hypersensitivity
penicillins
cephalosporins
imipenem-cross sensitivity with penicillins
nephrotoxicity
aminoglycosides-acute tubular necrosis
vancomycin-enhances toxicity of other drugs
skin rash-low hypersensitivity
vancomycin, aztreonam
ototoxicity
aminoglycosides: gentamycin
- erythromycin at high doses
hepatitis
isoniazid and rifampin, esp >50 yrs and EtOH
tetracyclines: pregnant women
phototoxicity
tetracyclines
fluoroquinolones: cirpofloxacin
kernicterus
sulfonamides
red man syndrome
vancomycin -infusion related toxicity
skin rash/stevens johnson
sulfonamides
gray baby syndrome
chloramphenicol
arthropathy
ciprofloxacin
peripheral neuropathy
isoniazid- slow acetylators
discoloration of body fluids
rifampin
optic neuritis
ethambutol
acute gout
ethambutol, pyrazinamide