antimicrobial pharm Flashcards
What 4 drugs cause nephrotoxicity?
Aminoglycosides, tetracyclines and cephalosporins, vancomycin
What 2 drugs cause hepatotoxicity(liver)?
Isoniazid and sulfonamides
What does neurotoxicity/ototoxicity cause?
eighth cranial nerve can be damaged
What is photosensitivity?
sensitivity to sun.
Cephalosporins are ——– and related to ——-.
semi-synthetic related to penicillins
aminoglycosides
anesthesia in past 48hrs-neuromuscular blockade, resp depression
What does sulfonamides cause?
Crystalluria and sulfa rash, immunosuppression
vancomycin causes what?
nephrotoxicity and otoxicity
what do u add to antibiotics to prevent the microbe from breaking down the antibiotic?
augmetin
what r the 4 types of organisms
bacteria, fungi, parasitic helminths, parasitic arthropods
what is the only thing that still kills bacteria
Alcohol
FUO
Fever of unknown origin
HAI
healthcare associated infection
how long does it take for a C & S result to come back
24-48 hrs
what is the presence and growth of a foreign organism?
infection
chemical that controls or eliminates living microorganisms
antibiotics
a gout drug that u can’t take with anything
probenecid
fastest you should ever run a pump
150mL/hr
medication made from mold
penicillins
usually end in cillin
pencillins
2 types of natural penicillins
penn G and Penn V
4 semisynthetic penicillins
cloxacillin, methicillin, amoxicillin, and ampicillin
what is exfoliative dermatitis
shed like a snake
what class of drugs cannot be mixed with any other drug beside probenecid
MAOI’s
what’s the normal IM needle syringe combo
22 guage 1 1/2 inch needle 3mL syringe
HPI
history of present illness
what 2 things do u encourage a person to take while on antibiotics
probiotics and yogurt with live cultures
what type of antibiotics are synthetic
chemical
what type of antibiotics kills growth
bacteriocidal
what type of antibiotics inhibits growth
bacteriostatic
what type of antibiotics treat large number of bacteria
broad-spectrum
what type of antibiotics only treat specific or few particular bacteria
narrow-spectrum
people with _____ are more at risk for allergic reactions
asthma
review nursing process in bn1
1
what is superinfection
a worse infection due to not taking all the medication as prescribed
1 electrolyte lost during vomitting and diarrhea
potassium
give an example of secondary infection
yeast infection related to antibiotics
if pt states they have a metallic taste in mouth after taking a medication what should we watch for
anaphylaxis
what is pseudomembranous colitis
diarrhea caused by antibiotic therapy
1 symptom of anaphylaxis
hypotension
steroids are all antineoplasic drug so check the
WBC
for nephrotoxicity what labs do you assess
BUN and Creatinine(increased shows renal complications)
for nephrotoxicity what do you assess and what is it a symptom of
smoky colored urine, symptom of kidney malfunction
what lab do u assess for coumadin
PT and INR
what lab do u assess for heparin
PTT
what do u assess for hepatotoxicity
skin color, ascites, INR
what is made in the liver
prothombin
INH is
Isoniazid
sulfonamides cause what 2 things
crystaluria, and immunosuppression
what 3 labs do u assess for the break down of red blood cells
bilirubin, AST, ALT
study the cranial nerves
a
What is the primary cause of ototoxicity
aminoglycosides
inflammation of the optic nerve is
optic neuritis
What is photosensitivity
skin is sensitive to the sun
what is photophobia
light is sensitive to eyes
what is medication is parenterally incompatible
penicillins
requires a peak and trough and given for pt s undergoing GI surgery to make colon sterile
kanamycin
this medication will burn the fire out of vein
gentamicin
usually end in mycin
aminoglycosides
medication used for UTI’s, burns, and ulcerative colitis
sulfonimides
what medication must be ran in at over an hour because it goes bad but cant be ran to fast cause can cause BP to drop and cause shock
vancomycin
what medication is given for GI infections, diverticulitis
metronidazole (flagyl)
what is the treatment for TB
last 6-12 months with a combo of 3 drugs isoniazid(INH), rifampin, and pyrazinamide for 2 months then INH and rifampin for 4 months
key med for antihelmintics
vermox
What drug causes neurotoxicity/ototoxicity?
Aminoglycosides
Besides aminoglycosides, neurotoxicity/ototoxicity can occur with _________.
Vancomycin
What 2 meds cause photo sensitivity?
tetracycline and sulfonamide