Antimicrobial Drugs and Drug Resistance Flashcards

1
Q

What is the spectrum of activity for Clindamycin?

A

MRSA, Gram positive, Anaerobes

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2
Q

What is the spectrum of activity for a 1st generation cephalosporin?

A

Gram Positive, Gram negative

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3
Q

What is the spectrum of activity for aminoglycosides?

A

Gram negative, Pseudomonas

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4
Q

List all the MOAs (Mechanism of Action) that are considered bacteriostatic

A

Inhibition of protein synthesis

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5
Q

Which MOA can be applied topically?

A

Disruption of plasma membrane function

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6
Q

Which MOA can cause nephrotoxicity (Toxic to Kidneys)?

A

Inhibition of protein synthesis

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7
Q

What are the methods of antibiotic resistance?

A

Altered target, Enzyme degradation, Efflux

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8
Q

What is the name of the enzyme that can render antimicrobials ineffective?

A

Beta-lactamase

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9
Q

What is the method of resistance that some mycobacteria posses?

A

Efflux pumps

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10
Q

As a veterinary technician, what is your role in prevention of antibiotic misuse?

A

Client education

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