Antimicrobial Drugs and Drug Resistance Flashcards
What is the spectrum of activity for Clindamycin?
MRSA, Gram positive, Anaerobes
What is the spectrum of activity for a 1st generation cephalosporin?
Gram Positive, Gram negative
What is the spectrum of activity for aminoglycosides?
Gram negative, Pseudomonas
List all the MOAs (Mechanism of Action) that are considered bacteriostatic
Inhibition of protein synthesis
Which MOA can be applied topically?
Disruption of plasma membrane function
Which MOA can cause nephrotoxicity (Toxic to Kidneys)?
Inhibition of protein synthesis
What are the methods of antibiotic resistance?
Altered target, Enzyme degradation, Efflux
What is the name of the enzyme that can render antimicrobials ineffective?
Beta-lactamase
What is the method of resistance that some mycobacteria posses?
Efflux pumps
As a veterinary technician, what is your role in prevention of antibiotic misuse?
Client education