Antimicrobial Chemotherapy Flashcards
Which antibiotic can inhibit peptidoglycan synthesis?
a) penicillin
b) erythromycin
c) ciprofloxacin
a)penicillin
Name 2 glycopeptides
vancomycin and teicoplanin
Which antibiotic is commonly known to cause C. diff
a) gentamicin
b) daptomycin
c) cephalosporins
Cephalosporins
What do glycopeptides target?
a) protein synthesis
b) assembly of peptidoglycan precursor
c) purine synthesis
b)assembly of peptidoglycan precursor
Which gram positive cocci is resistant against gentamicin?
streptococcus
What do macrolides and tetracylines target?
a) peptidoglycan synthesis
b) DNA synthesis
c) protein synthesis
c)protein synthesis
What 5 antibiotic classes target protein synthesis?
aminoglycosides macrolides tetracyclines oxazolidinone cyclic lipopeptide
What is given alongside trimethoprim in the treatment of UTI/chest infections?
sulphamethoxazole
Which protein synthesis inhibitor targets gram negative bacteria?
a) clarithromycin
b) teicoplanin
c) gentamicin
c)gentamicin
Which group of antibiotics target topoisomerase in inhibiting DNA synthesis?
a) fluroquinolones
b) cyclic lipopeptides
c) tertracylines
a)fluroquinolones
Which antibiotic can be used to replace penicillin in gram positive infection?
a) marcolides (erythromycin and clarithromycin)
b) oxazolidinones
c) ciprofloxacin
a)macrolides
What type of bacteria is levofloxacin used to treat?
a) gram negative
b) gram positive
c) curved bacilli
b)gram positive
Which protein synthesis inhibitors are effective against MRSA?
linezolid and daptomycin
Which polyene is used for serious fungal infection?
a) amphotericin B
b) nystatin
c) terbinafine
a)amphotericin B
What do Azoles target?
a) ergosterol synthesis
b) glucan polysaccharide synthesis
c) protein synthesis
a)ergosterol synthesis