Antimicrobial Chemotherapy

Question 1

Beta lactam antibiotics

Answer 1

Penicillin & cephalosporins

Question 2

Glycopeptides

Answer 2

Vancomycin and teicoplanin

Question 3

Inhibition of bacterial cell wall synthesis

Answer 3

Beta lactam antibiotics, glycopeptides, cycloserine and bacitracin

Question 4

Last steps of peptidoglycan synthesis is inhibited by?

Answer 4

Beta lactam drugs which is initiated by certain receptors known as penicillin binding proteins

Question 5

The early steps of peptidoglycan is inhibited by

Answer 5

Glycopeptides and cycloserine

Question 6

Beta lactam resistant staphylococci can be inhibited by

Answer 6

Vancomycin

Question 7

Interference with cell membrane function

Answer 7

Antibacterial agent and antifungal agents

Question 8

Antibacterial agents are

Answer 8

Polymyxin and colistin

Question 9

Antifungal agents

Answer 9

Amphotericin B , nystatin and imidazoles

Question 10

Agents acting on the 30s ribosomal subunit

Answer 10

Tetracycline and amino glycosides

Question 11

Amino glycosides

Answer 11

Gentamicin, streptomycin and amikacin

Question 12

Agents acting on the 50s ribosomal subunit

Answer 12

Macrolides (erythromycin, azithromycin) 
Lincomycin (clindamycin) 
Streptogramins 
Linezolid
Chloramphenicol
Fusidic acid

Question 13

Inhibition of rna synthesis through the strong binding to dna dependant rna polymerase

Answer 13

Eg: rifampin

Question 14

Inhibition of dna synthesis through blocking dna gyrase

Answer 14

Quinolones, novobiocin

Question 15

Inhibition of dihydrofolic acid reductase leading to inhibition of folic acid synthesis.

Answer 15

Examples include trimethoprim and pyrimethamine

Question 16

Inhibition of folic acid synthesis by competitive antagonism.

Answer 16

Eg sulphonamides

Question 17

The glycocalyx of ____ and ___ allows organisms to adhere strongly to the heart valves

Answer 17

Staphylococcus epidermidis , viridans streptococci