Antimicrobial

Question 1

Bacitracin is only used in ?

Answer 1

Limited to topical use bc of its marked nephrotoxicity

Question 2

Cycloserine used only in ?

Answer 2

Tuberculosis caused by organisms resistant to first line antituberculous drugs bc of neurotoxicity

Question 3

Treatment of Toxoplasmosis

Answer 3

Pyrimethamine + sulfadiazine (+ folinic acid)

Alternative: Pyrimethamine + clindamycin

Question 4

Rash(Stevens-Johnson syndrome) is related to the use of:

Answer 4

Anti-epileptic drugs (especially lamotrigine)
Allopurinol
Sulfa drugs
Penicillin

Question 5

Hemolysis in G6PD deficiency can be caused by

Answer 5

Isoniazid, sulfonamides, dapsone, primaquine, aspirin, ibuprofen, nitrofurantoin

Question 6

Aplastic anemia can be caused by

Answer 6

Carbamazepine, methimazole, NSAIDs, Benzene, Chloramphenicol, Propylthiouracil

Cant make new blood cell properly

Question 7

Sulfa drugs include:

Answer 7

Sulfonamide antibiotics
Sulfasalazine 
Probenecid, furosemide, Acetozolamide 
Celecoxib 
Thiazides 
Sulfonylureas (antidiabetic drugs)

Question 8

Photosensitivity is caused by:

Answer 8

Sulfonamides
Tetracyclines
Amiodarone
5-FU (fluorouracil: cancer treatment)

Question 9

Direct Coombs positive hemolytic anemia can be caused by

Answer 9

Penicillin, methyldopa, (cephalosporins pas sur)