Antimicrobial

Question 1

B lactam drugs

Answer 1

penicillin, cephalosporin, monobactam, carbapenem

Question 2

when is monobactam and carbapenem used?

Answer 2

They are B lactams, cell wall inhibitors, and they are considered as deserved drugs, as they are not used in first incidiance, and they are kept when resistance are there

Question 3

What is the type of action in beta lactam drugs

Answer 3

bacteriosidal

Question 4

What is the function of transpeptidase?

Answer 4

it is for maintain closeknit structure of the bacteria

Question 5

What does the B Lactam drugs effect?

Answer 5

Effect the cell wall, by inhibiting transpeptidase

Question 6

how can drug intereaction be beneficial in penicillin?

Answer 6

probenecid (antigout drug) competes with penecillin for organic acid transporter in proximal tubule and this increase half life of penecillin G

Question 7

what is penicillin G spectrum?

Answer 7

Narrow spectrum

Question 8

Is peneicillin G beta lactamase sensitive?

Answer 8

Yes

Question 9

Penecillin G is drug of choice if ther is no resistance to it

Question 10

What are Penecillin G uses?

Answer 10

Strept. pneumococcal, meningococcal and syphilis (treponema)

Question 11

adverse effect of penicillin G?

Answer 11

Pain at intra- muscular site and hypersensitivity reation (Important to know about hyperS.

Question 12

What is the point of semisynthetic pencillin?

Answer 12

to overcome the shortcoming of the natural penicillin

Question 13

what is example of acid resistant B lactam drug?

Answer 13

Penicillin V

Question 14

Is Penicillin V B lactamase sensitive?

Answer 14

Yes

Question 15

What is spectrum of activity in PENCILLIN V

Answer 15

Narrow spectrum

Question 16

What arethe uses of pencillin V?

Answer 16

Used for resperatory tract infections, Streptcoccal pharyngitis, Sinusitis, otitis media, rheumatic fever prohphylaxis, and less serious pneumococcal infection