Antimalarial Drugs Flashcards

1
Q

4 aminoquinolones

A

Chloroquine

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2
Q

Quinoline methanol

A

Mefloquine

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3
Q

Cinchona alkaloid

A

Quinine

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4
Q

Biguanide

A

Proguanil

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5
Q

Diaminopyramidine

A

Pyrimethamine

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6
Q

8 amino quinolones

A

Primaquine

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7
Q

Sulfonamide

A

Sulfadoxine

Sulfamethopyrazine

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8
Q

Antibiotics

A

Doxycycline

Clindamycin

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9
Q

Sesquiterpene lactones

A

Artesunate

Artemether

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10
Q

Amino alchohols

A

Lumefantrine

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11
Q

Naphtoquinone

A

Atovaquone

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12
Q

Naphthyridine

A

Pyronaridine

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13
Q

Chloroquine resistant uncomplicated falciparum malaria treatment

A
  1. Artesunate 100mg BD (4mg/kg/day) x 3days +

mefloquine 750 mg (15mg/kg) on 2nd day and 500 mg (10mg/kg) on 3rd day OR Sulfadoxine 1500 mg (25mg/kg) + pyrimethamine 75 mg (1.25mg/kg) single dose

  1. Quinine 600mg (10mg/kg) 8 hourly x 7 days + doxycycline 100. Mg daily x7 days OR clindamycin 600 mg 12 hourly x 7 days
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