Antikoagülanlar Flashcards

1
Q

What is the primary purpose of anticoagulants?

A

To prevent blood clot formation.

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2
Q

True or False: Anticoagulants are used to dissolve existing blood clots.

A

False.

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3
Q

Name one commonly used anticoagulant.

A

Warfarin.

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4
Q

What mechanism does heparin use to exert its anticoagulant effect?

A

Heparin enhances the activity of antithrombin III.

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5
Q

Fill in the blank: Anticoagulants are often prescribed for patients with __________.

A

thromboembolic disorders.

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6
Q

What are direct oral anticoagulants (DOACs)?

A

A class of anticoagulants that directly inhibit specific coagulation factors.

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7
Q

Which factor does rivaroxaban inhibit?

A

Factor Xa.

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8
Q

True or False: Anticoagulants require regular blood monitoring.

A

True (especially Warfarin).

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9
Q

What is the antidote for warfarin overdose?

A

Vitamin K.

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10
Q

Which anticoagulant is often used in hospitalized patients?

A

Unfractionated heparin.

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11
Q

What is the primary risk associated with anticoagulant therapy?

A

Increased risk of bleeding.

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12
Q

Name a contraindication for anticoagulant use.

A

Active bleeding.

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13
Q

What is the role of antithrombin in anticoagulation?

A

It inhibits thrombin and factor Xa.

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14
Q

Fill in the blank: The __________ test is used to monitor patients on warfarin.

A

INR (International Normalized Ratio).

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15
Q

What is dabigatran’s mechanism of action?

A

Direct thrombin inhibitor.

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16
Q

True or False: Anticoagulants can be used during pregnancy.

A

True (some are safer than others).

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17
Q

What is the significance of the ‘half-life’ of an anticoagulant?

A

It determines how long the drug remains active in the body.

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18
Q

Which anticoagulant is administered subcutaneously?

A

Low molecular weight heparins (e.g., enoxaparin).

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19
Q

What dietary considerations should be made when taking warfarin?

A

Consistent intake of vitamin K-rich foods.

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20
Q

What is fondaparinux?

A

A synthetic anticoagulant that selectively inhibits factor Xa.

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21
Q

True or False: All anticoagulants can be reversed.

A

False.

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22
Q

What is the purpose of using anticoagulants in atrial fibrillation?

A

To reduce the risk of stroke.

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23
Q

Which anticoagulant is often used for patients with mechanical heart valves?

A

Warfarin.

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24
Q

What are the potential side effects of anticoagulants?

A

Bleeding, bruising, and gastrointestinal issues.

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25
Q

What is the role of aPTT in anticoagulation therapy?

A

It monitors the effectiveness of heparin therapy.

26
Q

Name one advantage of direct oral anticoagulants over traditional anticoagulants.

A

No routine monitoring required.

27
Q

What is the mechanism of action for apixaban?

A

Direct factor Xa inhibitor.

28
Q

Fill in the blank: Anticoagulants should be used with caution in patients with __________.

A

liver disease.

29
Q

What is the role of the coagulation cascade in hemostasis?

A

It is a series of reactions that lead to clot formation.

30
Q

True or False: Anticoagulants are the same as antiplatelet drugs.

A

False.

31
Q

What is the primary goal of anticoagulation therapy?

A

To prevent thromboembolic events.

32
Q

What is the primary purpose of anticoagulants?

A

To prevent blood clot formation.

33
Q

True or False: Anticoagulants are used to dissolve existing blood clots.

A

False.

34
Q

Name one commonly used anticoagulant.

A

Warfarin.

35
Q

What mechanism does heparin use to exert its anticoagulant effect?

A

Heparin enhances the activity of antithrombin III.

36
Q

Fill in the blank: Anticoagulants are often prescribed for patients with __________.

A

thromboembolic disorders.

37
Q

What are direct oral anticoagulants (DOACs)?

A

A class of anticoagulants that directly inhibit specific coagulation factors.

38
Q

Which factor does rivaroxaban inhibit?

A

Factor Xa.

39
Q

True or False: Anticoagulants require regular blood monitoring.

A

True (especially Warfarin).

40
Q

What is the antidote for warfarin overdose?

A

Vitamin K.

41
Q

Which anticoagulant is often used in hospitalized patients?

A

Unfractionated heparin.

42
Q

What is the primary risk associated with anticoagulant therapy?

A

Increased risk of bleeding.

43
Q

Name a contraindication for anticoagulant use.

A

Active bleeding.

44
Q

What is the role of antithrombin in anticoagulation?

A

It inhibits thrombin and factor Xa.

45
Q

Fill in the blank: The __________ test is used to monitor patients on warfarin.

A

INR (International Normalized Ratio).

46
Q

What is dabigatran’s mechanism of action?

A

Direct thrombin inhibitor.

47
Q

True or False: Anticoagulants can be used during pregnancy.

A

True (some are safer than others).

48
Q

What is the significance of the ‘half-life’ of an anticoagulant?

A

It determines how long the drug remains active in the body.

49
Q

Which anticoagulant is administered subcutaneously?

A

Low molecular weight heparins (e.g., enoxaparin).

50
Q

What dietary considerations should be made when taking warfarin?

A

Consistent intake of vitamin K-rich foods.

51
Q

What is fondaparinux?

A

A synthetic anticoagulant that selectively inhibits factor Xa.

52
Q

True or False: All anticoagulants can be reversed.

A

False.

53
Q

What is the purpose of using anticoagulants in atrial fibrillation?

A

To reduce the risk of stroke.

54
Q

Which anticoagulant is often used for patients with mechanical heart valves?

A

Warfarin.

55
Q

What are the potential side effects of anticoagulants?

A

Bleeding, bruising, and gastrointestinal issues.

56
Q

What is the role of aPTT in anticoagulation therapy?

A

It monitors the effectiveness of heparin therapy.

57
Q

Name one advantage of direct oral anticoagulants over traditional anticoagulants.

A

No routine monitoring required.

58
Q

What is the mechanism of action for apixaban?

A

Direct factor Xa inhibitor.

59
Q

Fill in the blank: Anticoagulants should be used with caution in patients with __________.

A

liver disease.

60
Q

What is the role of the coagulation cascade in hemostasis?

A

It is a series of reactions that lead to clot formation.

61
Q

True or False: Anticoagulants are the same as antiplatelet drugs.

A

False.

62
Q

What is the primary goal of anticoagulation therapy?

A

To prevent thromboembolic events.