Antikoagülanlar Flashcards
What is the primary purpose of anticoagulants?
To prevent blood clot formation.
True or False: Anticoagulants are used to dissolve existing blood clots.
False.
Name one commonly used anticoagulant.
Warfarin.
What mechanism does heparin use to exert its anticoagulant effect?
Heparin enhances the activity of antithrombin III.
Fill in the blank: Anticoagulants are often prescribed for patients with __________.
thromboembolic disorders.
What are direct oral anticoagulants (DOACs)?
A class of anticoagulants that directly inhibit specific coagulation factors.
Which factor does rivaroxaban inhibit?
Factor Xa.
True or False: Anticoagulants require regular blood monitoring.
True (especially Warfarin).
What is the antidote for warfarin overdose?
Vitamin K.
Which anticoagulant is often used in hospitalized patients?
Unfractionated heparin.
What is the primary risk associated with anticoagulant therapy?
Increased risk of bleeding.
Name a contraindication for anticoagulant use.
Active bleeding.
What is the role of antithrombin in anticoagulation?
It inhibits thrombin and factor Xa.
Fill in the blank: The __________ test is used to monitor patients on warfarin.
INR (International Normalized Ratio).
What is dabigatran’s mechanism of action?
Direct thrombin inhibitor.
True or False: Anticoagulants can be used during pregnancy.
True (some are safer than others).
What is the significance of the ‘half-life’ of an anticoagulant?
It determines how long the drug remains active in the body.
Which anticoagulant is administered subcutaneously?
Low molecular weight heparins (e.g., enoxaparin).
What dietary considerations should be made when taking warfarin?
Consistent intake of vitamin K-rich foods.
What is fondaparinux?
A synthetic anticoagulant that selectively inhibits factor Xa.
True or False: All anticoagulants can be reversed.
False.
What is the purpose of using anticoagulants in atrial fibrillation?
To reduce the risk of stroke.
Which anticoagulant is often used for patients with mechanical heart valves?
Warfarin.
What are the potential side effects of anticoagulants?
Bleeding, bruising, and gastrointestinal issues.
What is the role of aPTT in anticoagulation therapy?
It monitors the effectiveness of heparin therapy.
Name one advantage of direct oral anticoagulants over traditional anticoagulants.
No routine monitoring required.
What is the mechanism of action for apixaban?
Direct factor Xa inhibitor.
Fill in the blank: Anticoagulants should be used with caution in patients with __________.
liver disease.
What is the role of the coagulation cascade in hemostasis?
It is a series of reactions that lead to clot formation.
True or False: Anticoagulants are the same as antiplatelet drugs.
False.
What is the primary goal of anticoagulation therapy?
To prevent thromboembolic events.
What is the primary purpose of anticoagulants?
To prevent blood clot formation.
True or False: Anticoagulants are used to dissolve existing blood clots.
False.
Name one commonly used anticoagulant.
Warfarin.
What mechanism does heparin use to exert its anticoagulant effect?
Heparin enhances the activity of antithrombin III.
Fill in the blank: Anticoagulants are often prescribed for patients with __________.
thromboembolic disorders.
What are direct oral anticoagulants (DOACs)?
A class of anticoagulants that directly inhibit specific coagulation factors.
Which factor does rivaroxaban inhibit?
Factor Xa.
True or False: Anticoagulants require regular blood monitoring.
True (especially Warfarin).
What is the antidote for warfarin overdose?
Vitamin K.
Which anticoagulant is often used in hospitalized patients?
Unfractionated heparin.
What is the primary risk associated with anticoagulant therapy?
Increased risk of bleeding.
Name a contraindication for anticoagulant use.
Active bleeding.
What is the role of antithrombin in anticoagulation?
It inhibits thrombin and factor Xa.
Fill in the blank: The __________ test is used to monitor patients on warfarin.
INR (International Normalized Ratio).
What is dabigatran’s mechanism of action?
Direct thrombin inhibitor.
True or False: Anticoagulants can be used during pregnancy.
True (some are safer than others).
What is the significance of the ‘half-life’ of an anticoagulant?
It determines how long the drug remains active in the body.
Which anticoagulant is administered subcutaneously?
Low molecular weight heparins (e.g., enoxaparin).
What dietary considerations should be made when taking warfarin?
Consistent intake of vitamin K-rich foods.
What is fondaparinux?
A synthetic anticoagulant that selectively inhibits factor Xa.
True or False: All anticoagulants can be reversed.
False.
What is the purpose of using anticoagulants in atrial fibrillation?
To reduce the risk of stroke.
Which anticoagulant is often used for patients with mechanical heart valves?
Warfarin.
What are the potential side effects of anticoagulants?
Bleeding, bruising, and gastrointestinal issues.
What is the role of aPTT in anticoagulation therapy?
It monitors the effectiveness of heparin therapy.
Name one advantage of direct oral anticoagulants over traditional anticoagulants.
No routine monitoring required.
What is the mechanism of action for apixaban?
Direct factor Xa inhibitor.
Fill in the blank: Anticoagulants should be used with caution in patients with __________.
liver disease.
What is the role of the coagulation cascade in hemostasis?
It is a series of reactions that lead to clot formation.
True or False: Anticoagulants are the same as antiplatelet drugs.
False.
What is the primary goal of anticoagulation therapy?
To prevent thromboembolic events.