Antihypertensives Medchem Flashcards
1
Q
Bradykinin not broken down
A
Higher levels of bradykinin particularly in lungs
Dry cough
2
Q
Allostery of CCB
Verapamil
Diltiazem
1,4 -dihydropyridines
A
Verapamil + Diltiazem = NEGATIVE allosteric effect
Diltiazem + 1,4-dihydropyridines = POSITIVE allosteric effect