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antihistamines - 1st/2nd generation > antihistamine H1 blockers > Flashcards

antihistamine H1 blockers Flashcards

0
Q

Benadryl diphenhydramine

INDICATIONS (8)

A 
allergy   pruritus
cold       vertigo
cough    leg cramp
insomnia
parkinson's
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1
Q

benadryl diphenhydramine

MECHANISM

A

blocks histamine receptor H1

anticholinergic

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2
Q

Benadryl diphenhydramine

CAUTION

A 
drowsiness
urinary retention
dry secretions
constipation
avoid in COPD and glaucoma
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3
Q

claritin loratadine

MECHANISM

A

long lasting
non-sedating antihistamine
H1 blocker

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4
Q

claritin loratadine

INDICATIONS

A

allergic rhinitis

urticaria

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5
Q

claritin loratadine

CAUTION

A

weak anticholinergic
caution with asthma
some fatigue and headache
available in claritin D (dries mucosa)

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6
Q

clarinex desloratadine

MECHANISM

A

active isomer of loratidine (active drug)

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7
Q

clarinex desloratadine

INDICATIONS

A

allergic rhinitis

urticaria

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8
Q

clarinex desloratadine

CAUTIONS

A 
weak anticholinergic
caution with asthma
some fatigue, headache
available as claritin D
only 5mg/d
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9
Q

Periactin cyproheptadine

MECHANISM

A

block H1 and serotonin

5HT2 receptors

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10
Q

Periactin cyproheptadine

INDICATIONS

A

allergic rhinitis
pruritis
anorexia
anorgasmy

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11
Q

Periactin cyproheptadine

CAUTIONS

A 
depression    abuse potential
fatigue
asthma, ileus, COPD
glaucoma
urinary retention (elderly)
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12
Q

phenergan promethazine

MECHANISM

A

blocks H1 and dopamine receptor

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13
Q

phenergan promethazine

INDICATIONS

A

pruritis
cough
motion sickness
antiemetic

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14
Q

phenergan promethazine

CAUTIONS

A

may block effects of levodopa
depression, fatigue
asthma, ileus, COPD
glaucoma, urinary retention (eldery)

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15
Q

Allegra Fexofenadine

MECHANISM

A

blocks H1
non sedating
the active metabolite of seldane

16
Q

Allegra Fexofenadine

INDICATIONS

A

allergic rhinitis

17
Q

Allegra Fexofenadine

CAUTIONS

A

not to be used with patients with seldane hypersensitivity

some drowsiness

18
Q

atarax hydroxyzine ——— visitril hydroxyzine pamoate
MECHANISM

A

H1 blocker

increases effectiveness of narcotics (parenteral form)

19
Q

atarax hydroxyzine ——— visitril hydroxyzine pamoate
INDICATIONS

A

anxiety
insomnia
pruritus

20
Q

atarax hydroxyzine ——— visitril hydroxyzine pamoate
CAUTIONS

A

drowsiness

thickened bronchial secretions

21
Q

Zyrtec cetirizine

MECHANISM

A

H1 blocker

the active metabolite of hydroxyzine

22
Q

Zyrtec cetirizine

INDICATIONS

A

allergic rhinitis

Urticaria

23
Q

Zyrtec cetirizine

CAUTIONS

A

Drowsiness

antihistamines - 1st/2nd generation (4 decks)

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