Antihelmintic, Antiviral Drugs

Question 1

What is the route of administration of pyrantel?

Answer 1

Oral

Question 2

What is the pregnancy category of Ribavirin (Virazole)

Answer 2

Category X: no to pregnant women

Question 3

How long are anthelmintic drugs given?

Answer 3

1-3 days

Question 4

Administration of medication that is based on practitioner’s judgment

Answer 4

Empiric therapy

Question 5

This is the drug that crosses the breast milk that is why it is contraindicated to lactating women

Answer 5

Praziquantel

Question 6

Antiviral drug in IV form only

Answer 6

Foscarnet

Question 7

Composed of either a DNA or RNA inside a protein coat

Replicates inside the host cell

Answer 7

Virus

Question 8

This drug is a long-term viral treatment

Answer 8

Ganciclovir (Cytovene)

Question 9

How does Sulfonamides work?

Answer 9

Inhibit growth by preventing bacterial synthesis of folic acid interrupting synthesis of DNA and RNA

Question 10

For pinworms and roundworms

Answer 10

Pyrantel

Question 11

Type of Reverse Transcriptase Inhibitor that blocks reverse transcriptase enzymes

Answer 11

Nucleoside Reverse Transcriptase Inhibitor

NRTI’s

Question 12

Used to treat infection caused by hookworm, roundworm, whipworm

Answer 12

Thiabendazole

Question 13

What is Albendazole used for?

Answer 13

Lesions caused by pork tapeworm and cystic disease of liver, lungs

Question 14

What is the mechanism of action of Non-nucleoside Reverse Transcriptase Inhibitors (NNRTI’s)?

Answer 14

It binds with reverse transcriptase enzyme and prevents conversion of HIV RNA into HIV DNA

Question 15

What are the goals of Highly active antiretroviral therapy (HAART)?

Answer 15

Decrease viral load to undetectable levels
Preserve and increase CD4 T cells
Prevent resistance
Have client in good clinical condition
Prevent secondary infections and cancers

Question 16

Four groups of Helminths

Answer 16

Cestodes(tapeworms)
Trematodes(flukes)
Intestinal nematodes (roundworms)
Tissue-invading nematodes (tissue roundworms)

Question 17

What cell does HIV attack?

Answer 17

CD4 T cells

Question 18

Caution for Amantadine

Answer 18

Renal impairment

Question 19

What are the contraindications of anthelmintic drugs?

Answer 19

• Pregnancy
• Allergy
• Lactation

Question 20

This antiviral drug can cause severe renal toxicity and granulocytopenia

Answer 20

Cidofovir (Vistide)

Question 21

Imipenem, Meropenem, Ertapenem, and Doripenem are all example medications of __________

Answer 21

Carbapenem (Beta Lactam)

Question 22

Used to treat uncomplicated influenza infections

Answer 22

Oseltamivir (Tamiflu)

Question 23

Children who start anthelmintic therapy need to have good nutrition and proper hydration to avoid?

Answer 23

Dehydration.

It will cause them diarrhea which is also good to remove the worms

Question 24

It is effective against most aerobic and anaerobic bacteria except P. Aeruginosa

Answer 24

Chloramphenicol

Question 25

What is the mechanism of action of Nucleoside Reverse Transcriptase Inhibitors (NRTI’s)

Answer 25

Block reverse transcriptase enzyme

Question 26

It blocks protease activity within the HIV virus (later stage)

Answer 26

Protease Inhibitors

Question 27

It is used for treating Influenza A and is only used in pregnancy and lactation ONLY if the benefits outweigh the risk as it crosses breast milk and the placental barrier

Answer 27

Amantadine (Symmetrel)