ANTIGLOMERULAR BM MEMBRANE AB SYNDROME

Question 1

GOODPASTURE’S SYNDROME

Answer 1

AB AGAINS BM COLLAGEN TYPE 4
MALES> FEMALES
MORE COMMON IN SMOKERS

Question 2

GOODPASTURE’S AND KIDNEYS

Answer 2

IN 10% THERE IS NO RENAL INVOLVEMENT

Question 3

GOODPASTURE’S TREATMENT

Answer 3

CONCURRENT PLASMAPHERESIS, STEROIDS AND CYCLOPHOSPHAMIDE
PLASMAPHERESIS REMOVES AB
STEROIDS AND CYTOXAN PREVENTS NEW AB