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INFECTOLOGIA > Antifungicos > Flashcards

Antifungicos Flashcards

1
Q

TRATAMINETO MINIMO Antifúngicos

A

4 SEMANAS
LARGA DURACION

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2
Q

EXTRACELULARES

A

POLIENOS
AZOLES

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3
Q

INTRACELULARES

A

NUCLEOSIDOS
BENZOFURANOS
EQUINOCANDINAS

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4
Q

POLIENOS
LUGAR DE ACCION
DIVISIONES

A

ALTERAN LA PERMEABILIDAD DE MEMBRANA
1- ANFOTERICINA B
2- NISTATINA

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5
Q

ANFOTERICINA B
USO EN:
ADMINISTRACION:
TIPOS:
PTE:

A

PARTE DE POLIENOS
ALTERA LA PERMEABILIDAD
USO EN: MICOSIS PROFUNDAS
(HISTOPLASMOSIS, CRIPTOCOCOSIS, MUSCORMICOSIS, ASPERGILUS)
ADMINISTRACION: EV Y GOTEO
TIPOS:
1- DESOXICOLATO: NEFROTOXICO, 1 MES DE TTO
2- LIPOSOMAL: NO ES TOXICO, 1 SEMANA
PTE: INMUNOCOMPROMETIDO

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6
Q

NISTATINA
USO EN:
ADMINISTRACION:
TIPOS:
PTE:

A

PARTE DE POLIENOS
ALTERAN LA PERMEABILIDAD
EN MUCOSIS SUPERFICIALES
CANDIDIASIS VAGINALES RESISTENTES A FLUCONAZOL
PTE: INMUNOCOMPETENTES

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7
Q

AZOLES
ACCION
TIPOS

A

INHIBEN LA SINTESIS DE ERGOSTEROL (M)
1- IMIDAZOLES
2- TRIAZOLES

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8
Q

IMIDAZOLES
USO EN:
ADMINISTRACION:
TIPOS:
PTE:

A

USO EN: MICOSIS SUPERFICIALES
ADMINISTRACION: SHAMPO, CREMAS
TIPOS: MICONAZOL, CLOTRIMAZOL (FOLICULITIS), QUETONAZOL
PTE: CON TINA, DERMATOFITOS, INTERTRIGOS, VULVITIS

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9
Q

TRIAZOLES
TIPOS:

A

ITRACONAZOL

FLUCONAZOL

VORICONAZOL/POSACONAZOL

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10
Q

ITRACONAZOL
USO EN:
ADMINISTRACION:
TIPOS:
PTE:

A

INHIBE LA SINTESIS DE ERGOSTEROL
PARTE DE LOS AZOLES
USO EN: MUCOSIS SUPERFICIALES (IDEPRI) Y PROFUNDAS (ICOMP)
ADMINISTRACION: 6 MESES
COMPLEMETRARIO AL DAR EL ALTA
PTE: COMPETENTES (PROFUNDAS) Y DEPRIMIDOS (SUPERFICIALES)

ONICOMICOSIS

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11
Q

FLUCONAZOL
USO EN:
ADMINISTRACION:
TIPOS:
PTE:

A

INHIBE LA SINTESIS DE ERGOSTEROL
PARTE DE LOS AZOLES

USO EN: CANDIDIASIS ESOFAGICA (EV), MUCHA RESISTENCIA. ONICOMICOSIS
ADMINISTRACION: VO, EV
PTE: INMUNODEPRIMIDO

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12
Q

VORICONAZOL/POSACONAZOL
USO EN:
ADMINISTRACION:
TIPOS:
PTE:

A

USO EN: MUCOSIS PROFUNDAS (ASPERGILLUS Y TUMORES HEMATOLOGICOS)
ADMINISTRACION: VO, EV
PTE: INMUNOCOMPROMETIDOS

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13
Q

NUCLEOSIDOS
USO EN:
ADMINISTRACION:
TIPOS:
PTE:

A

INTRACELULAR
INHIBEN SINTESIS DE ACIDOS NUCLEICOS
USO EN: MICOSIS PROFUNDA
ADMINISTRACION: JUNTO A ANFOTERICINA
TIPOS: 5-FLUORSITOCINA
PTE: CASOS GRAVES

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14
Q

BENZOFURANOS
USO EN:
ADMINISTRACION:
TIPOS:
PTE:

A

INTRACELULARES
INHIBEN MITOSIS
USO EN: MICOSIS SUPERFICIALES (ONICOMICOSIS DE DIFICIL TTO)
ADMINISTRACION:
TIPOS: GRISEOFULVINA
PTE: MUCHOS EA

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15
Q

EQUINOCANDINAS
USO EN:
ADMINISTRACION:
TIPOS:
PTE:

A

INTRACELULARES
FRENA SINTESIS DE B GLUCANO DE LA PARED
USO EN: MICOSIS PROFUNDAS
EN CANDIDAS
ADMINISTRACION: EA APLASIA MEDULAR
TIPOS: CASPOFUNGINA
PTE: INMUNOCOMPROMETIDOS

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INFECTOLOGIA (5 decks)

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