Antifungal/Protozoal Flashcards

1
Q

Fungal infections

A

mycoses

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2
Q

fungal skin infections

A

dermatophytes

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3
Q

THRUSH

A

candida albicans; oral candidiasis

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4
Q

how can thrush happen?

A

follows antibiotic therapy; antineoplastics; immunosuppressants (corticosteroids)

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5
Q

endings for fungal infections

A

Fungin

azole

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6
Q

Polyenes

A

amphotericin B & nystatin

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7
Q

Imidazoles & triazoles

A

ketoconazole, fluconazole

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8
Q

Premedicate with what for amphotericin B?

A

Antiemetics
Antihistamines
Antipyretics
Corticosteroids

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9
Q

What to monitor for IV infusion?

A

I/O

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10
Q

Monitor for therapeutic effects:

A

Easing of symptoms
improved energy levels
Normal V/S including temperature

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11
Q

Amphotericin B drug interactions

A

Digitalis glycosides
Nephrotoxic drugs
Thiazine diuretics (severe hypokalemia)

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12
Q

Amphotericin B indications

A

systemic infections with broad spectrum

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13
Q

Caspofungin indications

A

invasive aspergillosis

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14
Q

fluconazole indications

A

vaginal candiadis

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15
Q

nystatin indications

A

oral candiasis & topical

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16
Q

terbinafine indications

A

onychomycosis (fungal infection of fingernail/toenail)
athletes foot (tinea pedis)
jock itch (tinea cruris)
ringworm (tinea corporis)

17
Q

voriconazole indications

A

invasive aspergillosis

18
Q

terbinafine (laminal) long term therapy for toenail infection & finger nail

A

10 weeks

4 weeks

19
Q

voriconazole report

A
Bleeding
Bruising
Soft-tissue swelling
dark urine
persistent nausea/diarrhea
yellow sin/eyes
20
Q

voriconazole avoid what?

A

driving @ night

women–contraceptives

21
Q

monitor what with antifungals?

A

CBC & hematocrit for bone marrow suppression