Antiepileptic Agents Flashcards
Hydantoins like phenytoin work as:
Drug for treating generalized seizures
Stabilize nerve membrane throughout CNS directly
Stabilize nerve membrane in two ways
A+B
D
Use for treat seizures panic attack,restless leg movement:
Ethosuximide
Phenobarbital
Diazepam
Valproic acid
C
What is the mechanism of action ethosuximide?
Suppress the abnormal electrical activity in the brain associated with absence of seizures.
Drug for treating parties seizure:
Valproic acid
Carbamazepine
Levodopa
Clozapine
B
…………is associated with liver toxicity and can cause CNS effects
Valproic acid (which increase GABA receptor)
Barbiturates(like phenobarbital) can use as:
Anxiolytics and hypnotics
Antiepileptics agents
Antidepressant
A+b
D
How carbamazepine stabilize nerve membrane directly:
Increase the activity of GABA
Increase GABA activity at inhibitory receptor
Altering NA +/Ca + channel
C
Succinimides like(ethosuximide)act as:
Drug for treating generalized seizures
Antimanic drugs
Drug that modulate inhibitory transmitter GABA
A