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Tx Wes Clinical Guide > Antiemetics > Flashcards

Antiemetics Flashcards

1
Q

Droperidol Receptor

A

D2

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2
Q

Brand name for Droperidol

A

Inapsine

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3
Q

Droperidol dose

A

0.626 mg

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4
Q

Droperidol: Onset and Duration

A

Onset: 1-5 mins
Duration: 2 - 3 hours

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5
Q

Brand Name for Promethazine

A

Phenergan

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6
Q

Promethazine Receptor

A
  • Histamine (H1)
  • Muscarinic
  • Dopamine
  • Medullary Vomiting Center
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7
Q

Promethazine dose

A

6.25 - 25 mg

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8
Q

Promethazine Onset and Duration

A

Onset: 1-5 minutes
Duration: 4-6 hours

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9
Q

Brand name of Ondansetron

A

Zofran

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10
Q

Ondansetron Receptor

A

5-HT3

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11
Q

Ondansetron dose

A

4 mg

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12
Q

Ondansetron Onset and Duration

A

Onset: 10 mintes
Duration: 4-9 hours

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13
Q

Brand name for Dexmethasone

A

Decadron

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14
Q

Dexmethasone Receptor

A

Glucocorticoid Receptor (GR)

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15
Q

Dexmethasone Dose

A

4 mg

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16
Q

Dexmethasone onset and duration

A

Onset: 10 - 30 minutes
Duration: 2- 10 minutes

17
Q

Brand name for Metoclopramide

A

Reglan

18
Q

Metoclopramide Receptor

A
  • D2
  • 5-HT3
19
Q

Metoclopramide Dose

A

10 - 20 mg

20
Q

Metoclopramide Onset and Duration

A

Onset: 10 mins
Duration: 2 hours

21
Q

Scopalamine Receptor

A

Muscarinic Antagonist

22
Q

Scopalamine dose

A

Patch (0.3 - 0.65 mg)

23
Q

Scopalamine Onset and Duration

A

Onset: 2-4 hours
Duration: 72 hours

24
Q

Propofol Anti-emtic Receptor

A
  • GABA (stimultes)
  • 5-HT3 (reduces)
25
Q

Propofol Anti-emetic dose

A
  • 10 - 15 mg IV
  • Followed by 10 mcg/kg/min infussion
26
Q

PONV Risk Factors

A
  • Female
  • Age > 40
  • Hx PONV or Motion Sickness
  • Vertigo
27
Q

Surgical PONV Risk Factors

A
  • Laparoscopy
  • Major Breast
  • Strabismus
  • Intraocular
  • Middle Ear
  • Tonsils
  • Adenoids
  • Neuro (Intracranial)
  • Gynecologic
  • Testicular
  • Scrotum
  • Kidney Stones
28
Q

PONV Treatment Algorithm

Patient has 0 risk factors. What is the % chance of PONV and Treatment?

A
  • 10 %
  • Non-Pharmacological
29
Q

PONV Treatment Algorithm

Patient has 1 risk factors. What is the % chance of PONV and Treatment?

A
  • 20%
  • 1 drug
30
Q

PONV Treatment Algorithm

Patient has 2 risk factors. What is the % chance of PONV and Treatment?

A
  • 40%
  • 2 drugs
31
Q

PONV Treatment Algorithm

Patient has 3 risk factors. What is the % chance of PONV and Treatment?

A
  • > 60%
  • 3+ drugs

Tx Wes Clinical Guide (24 decks)

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