ANTIDYSRHYTHMIC Meds Flashcards
Class I A prototype antidysrhythmic
Procainamide
Other meds:
Quinidine
Disopyramide
Class I B prototype antidysrhythmic
Lidocaine
Other meds:
Mexiletine
Phenytoin
Class I C prototype antidysrhythmic
Propafenone
Other med:
Flecainide
Class II ANTIDYSRHYTHMIC Prototype
Propranolol
Other meds:
Esmolol
Acebutolol
Class III ANTIDYSRHYTHMIC Prototype
Amiodarone
Other meds: Sotalol Ibutilide Dofetilide Dronedarone
Class IV ANTIDYSRHYTHMIC Prototype
Verapamil
Other med: Dilitiazem
What is the action of Class I A antidysrhythmics?
Slows impulse conductions to atria/ventricles/His-Purkinje system
Delays repolarization
What is the therapeutic outcome of class I A antidysthymic meds?
Supraventricular tachycardia
Ventricular tachycardia
Atrial flutter
A-Fib
In class I B antidysrhythmic meds what actions occur in the atria/ventricles/His-Purkinje system?
Decrease electrical conduction
Decrease automaticity
Increase repolarization rate
What is Class I B antidysrhythmic meds therapeutic effect?
Short term use for ventricular dysrhythmias
What is the actions of Class I C antidysrhythmic meds?
Decrease conduction velocity in atria/ventricles/His-Purkinje system
& Delays ventricular repolarization
What is the therapeutic use of Class I C antidysrhythmic meds?
SVT
What is the action of Class II antidysrhythmic meds?
Decreases:
Heart rate/ Automaticity through SA node/ Velocity of conduction through AV node/ Myocardial contractility/ Atrial ectopic stimulation
What are the therapeutic uses for Class II antidysrhythmic meds?
A-Fib/ Atrial flutter/ Paroxysmal SVT/ Hypertension/ Angina/ PVCs/ Severe recurrent ventricular tachycardia/ Exercise-induced tachydysrhythmias/ Paroxysmal atrial tachycardia
What are the other antidysrhythmic medications used?
Digoxin & Adenosine
What is the action of Class III antidysrhythmic meds?
Delays repolarization/ Prolongs action potential/ Reduces SA node automaticity/ Reduces contractility & conduction in AV node, ventricles, His- Purkinje system/ Dilates coronary vessels
What is the therapeutic uses for Class III antidysrhythmic meds?
Oral admin: Conversion of A-Fib
Recurrent ventricular fibrillation/ Recurrent ventricular tachycardia/ atrial flutter using Dronedarone, Sotalol, Dofetilide, Ibutilide
What is the action of Class IV CCBs?
Decreases heart rate & contraction force/ Slows conduction rate of AV & SA nodes/ Promotes calcium blockages in the heart
What is the therapeutic uses for Class IV antidysrhythmic meds?
Control ventricular rate in A-Fib & flutter/ SVT/ Hypertension/ Angina pectoris
What does Adenosine do?
Decreases electrical conduction through AV node & decrease automaticity in SA node
What is Adenosine used for?
Paroxysmal SVT/ Wolff-Parkinson-White syndrome
