Antidepressants, Antipsychotics

Question 1

Fluoxetine

Answer 1

Prozac, SSRI, Longest half life

Question 2

Sertraline

Answer 2

Zoloft, SSRI, high risk for GI disturbances

Question 3

Peroxetine

Answer 3

Paxil, SSRI, highly protein bound, shortest half life

Question 4

Fluvoxamine

Answer 4

Luvox, D/C for fulminant hepatic failure, used for OCD

Question 5

Citalopram

Answer 5

Celexa, SSRI, Fewest drug drug interactions

Question 6

Escitalopram

Answer 6

Lexapro, SSRI, levo enantiomer of Citalopram

Question 7

Vortioxetine

Answer 7

Brintellix, SSRI, 5HT7 - improved cognition, motivation

Question 8

Venlafaxine

Answer 8

Effexor, SNRI, some use in ADHD, GAD. Different effect by dosing: Serotonergic (300)

Question 9

Duloxetine

Answer 9

Cymbalta, SNRI, often used for neuropathic pain, fibromyalgia. Safe up to 120 mg.

Question 10

Bupropion

Answer 10

Welbutrin, norepinephrine/dopamine reuptake inhibitor, antidepressant, lack of sexual side effects, some efficacy for ADHD, lowers seizure threshold

Question 11

Trazadone

Answer 11

Desyrel, serotonin receptor antagonist/agonist, antidepressant, lack of sexual side effects, does not affect REM, priapism

Question 12

Mirtazapine

Answer 12

Remeron, alpha 2 adrenergic receptor antagonist, useful for refractory depression

Question 13

Amitryptiline

Answer 13

Elavil, TCA, tertiary amine, chronic pain/migraines/insomnia

Question 14

Imipramine

Answer 14

Tofranil, TCA, tertiary amine, enuresis

Question 15

Clompiramine

Answer 15

Anafranil, TCA, tertiary amine, most serotonin specific, useful for OCD

Question 16

Doxepin

Answer 16

Sinequan, TCA, tertiary amine, chronic pain/sleep aid

Question 17

Nortryptiline

Answer 17

Pamelor, TCA, secondary amine, least likely to cause orthostatic HTN

Question 18

Desipramine

Answer 18

Norpramine, TCA, secondary amine, least anticholinergic

Question 19

Amoxapine

Answer 19

Asendin, tetracyclic

Question 20

Maprotiline

Answer 20

Ludiomil, tetracyclic

Question 21

Phenelzine

Answer 21

Nardil, MAOI

Question 22

Tranylcypromine

Answer 22

Parnate, MAOI

Question 23

Isocarboxid

Answer 23

Marplan, MAOI

Question 24

Chlorpromazine

Answer 24

Thorazine, typical antipsychotic, low potency, orthostatic HTN, bluish skin, photosensitivity

Question 25

Thioridazine

Answer 25

Mellaril, typical antipsychotic, low potency

Question 26

Loxapine

Answer 26

Loxitane, typical antipsychotic, mid potency

Question 27

Thiothixene

Answer 27

Navane, typical antipsychotic, mid potency

Question 28

Trifluoperazine

Answer 28

Stelazine, typical antipsychotic, mid potency

Question 29

Perphanazine

Answer 29

Trilafon, typical antipsychotic, mid potency

Question 30

Haloperidol

Answer 30

Haldol, typical antipsychotic, high potency, decanoate form available

Question 31

Fluphenazine

Answer 31

Prolixin, typical antipsychotic, high potency, deconoate form available

Question 32

Pimozide

Answer 32

Orap, typical antipsychotic, high potency

Question 33

Clozapine

Answer 33

Clozaril, atypical antipsychotic, more efficacious, lowers risk of suicide

Question 34

Risperidone

Answer 34

Risperdal, atypical antipsychotic, can increase prolactin

Question 35

Quetiapine

Answer 35

Seroquel, atypical antipsychotic

Question 36

Olanzapine

Answer 36

Zyprexa, atypical antipsychotic

Question 37

Ziprasidone

Answer 37

Geodon, atypical antipsychotic

Question 38

Aripiprazole

Answer 38

Abilify, atypical antipsychotic

Question 39

Paliperidone

Answer 39

Invega, atypical antipsychotic

Question 40

Asenapine

Answer 40

Saphris, atypical antipsychotic

Question 41

Iloperidone

Answer 41

Fanapt, atypical antipsychotic